2-((Difluoromethyl)thio)benzo[d]thiazole CAS 943-08-8
| CAS No. | 943-08-8 |
| Molecular Formula | C8H5F2NS2 |
| Molecular Weight | 217.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-((Difluoromethyl)thio)benzo[d]thiazole (CAS 943-08-8), molecular formula C8H5F2NS2 and molecular weight 217.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-((Difluoromethyl)thio)benzo[d]thiazole (C8H5F2NS2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5F2NS2 |
| Molecular Weight | 217.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Difluoromethyl Standards
- 3-(Difluoromethyl)benzo[d]thiazole-2(3h)-thione (CAS 358365-85-2)
- n-(4-((Difluoromethyl)thio)phenyl)acetamide (CAS 24933-63-9)
- 3-(Difluoromethyl)-4-(propylthio)aniline (CAS 1342776-28-6)
- (S)-1-(4-(difluoromethyl)-3-fluorophenyl)-2-methylpropan-1-amine (CAS 1212940-91-4)
- (S)-1-(4-(difluoromethyl)-3-fluorophenyl)butan-1-amine (CAS 1213171-89-1)
- (R)-1-(4-(difluoromethyl)-3-fluorophenyl)-2-methylpropan-1-amine (CAS 1213843-31-2)
- (R)-1-(4-(difluoromethyl)-3-fluorophenyl)butan-1-amine (CAS 1213970-14-9)
- 3-(Difluoromethyl)-4-(2-methoxyethoxy)aniline (CAS 1341103-02-3)
Recommended Standards
- 1-Pentyl-1H-indole-2,3-dione (CAS 4290-90-8)
- 2-(1,3-Dioxan-2-ylethyl)benzonitrile (CAS 951890-27-0)
- 1-Pentanoylindolin-2-one (CAS 57989-34-1)
- 2-(1H-Indol-3-yl)pentanoic acid (CAS 91957-23-2)
- 3-[(4-methoxyphenyl)methoxy]propanenitrile (CAS 791067-67-9)
- 1-Cyclooctyl-3-mesityl-1H-imidazol-3-ium chloride (CAS 1583244-05-6)
- 2-Amino-3-cyclopropoxy-N-methylisonicotinamide (CAS 1243318-19-5)
- 4-Methoxyphenyl 3,3,3-trifluoropropyl sulfide (CAS 1779129-46-2)
- 2-Chloro-4-[2-(1-methyl-piperidin-2-yl)-ethyl]-pyridine (CAS 1361115-30-1)
- Methyl 3-amino-6-bromo-5-chloropyrazine-2-carboxylate (CAS 14340-25-1)
- 7-(Chloromethyl)-12-methyltetraphene (CAS 13345-62-5)
- Estradiol Valerate Impurity 19 (CAS CATO-C4X-284219)
- 6,7-Dichloro-8-methoxy-2-(trifluoromethyl)quinazolin-4(3H)-one (CAS 50419-71-1)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
Why CATO?
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