ethyl 2,2-difluoro-2-(quinolin-6-yl)acetate CAS 943541-40-0
| CAS No. | 943541-40-0 |
| Molecular Formula | C13H21F2NO2 |
| Molecular Weight | 261.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), ethyl 2,2-difluoro-2-(quinolin-6-yl)acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies ethyl 2,2-difluoro-2-(quinolin-6-yl)acetate (CAS 943541-40-0), a certified reference material (molecular formula C13H21F2NO2, MW 261.31 g/mol) for analytical method development and quality control.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, ethyl 2,2-difluoro-2-(quinolin-6-yl)acetate is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 261.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C13H21F2NO2 |
| Molecular Weight | 261.31 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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- (OC-6-33)-Bis[1-[2-(hydroxy-κO)-5-methylphenyl]ethanonato-κO](1,10-phenanthroline-κN1,κN10)cobalt (CAS 1275614-75-9)
- 1,4-Dimethoxy-2,3-dimethylbenzene (CAS 39021-83-5)
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