8-Chloro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-boronic Acid Pinacol Ester CAS 943994-43-2
| CAS No. | 943994-43-2 |
| Molecular Formula | C14H17BClNO4 |
| Molecular Weight | 309.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 309.55 g/mol gives 8-Chloro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-boronic Acid Pinacol Ester distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
8-Chloro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-boronic Acid Pinacol Ester (CAS 943994-43-2), molecular formula C14H17BClNO4 and molecular weight 309.55 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 8-Chloro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-boronic Acid Pinacol Ester (C14H17BClNO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 8-Chloro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-boronic Acid Pinacol Ester under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H17BClNO4 |
| Molecular Weight | 309.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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- n-Hydroxy-3-(4-methoxyphenyl)propanamide (CAS 67363-26-2)
- 2-Methylbenzo[b]thiophene 1-oxide (CAS 33945-86-7)
- Tert-butyl ethyl(piperidin-2-ylmethyl)carbamate (CAS 1260651-30-6)
- 2-Bromo-6-isopropyl-7,8-dihydro-4H-pyrazolo[1,5-d][1,4]diazepin-5(6H)-one (CAS 2770250-96-7)
- 1-Difluoromethoxy-2-nitro-5-(trifluoromethoxy)benzene (CAS 1804880-87-2)
- (R)-3-Hydroxy-2-benzylpropanoic acid Ethyl ester (CAS 87884-40-0)
- 3,5-Dimethyl 2,6-dimethyl-4-(quinolin-2-yl)-1,4-dihydropyridine-3,5-dicarboxylate (CAS 50672-80-5)
- Peptide Impurity 09 X TFA Salt (CAS CATO-CPTD788809)
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