1-Methyl-5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazole CAS 944273-42-1
| CAS No. | 944273-42-1 |
| Molecular Formula | C12H11F3N2 |
| Molecular Weight | 240.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Methyl-5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazole (CAS 944273-42-1), molecular formula C12H11F3N2 and molecular weight 240.22 g/mol, is a CATO reference standard with documented purity and traceability.
1-Methyl-5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazole (C12H11F3N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11F3N2 |
| Molecular Weight | 240.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 1-(4-Nitrophenyl)-1H-benzo[d][1,2,3]triazole (CAS 4490-51-1)
- 1-Morpholino-2-(4-nitro-1H-pyrazol-1-yl)ethan-1-one (CAS 482573-95-5)
- 1-(4-(Aminomethyl)-4-hydroxypiperidin-1-yl)-3,3,3-trifluoropropan-1-one (CAS 2001227-86-5)
- 2-(1H-imidazol-1-yl)-8-nitroquinoline (CAS 330663-15-5)
- 6-((Naphthalen-1-ylmethyl)thio)-1,2,4-triazine-3,5(2H,4H)-dione (CAS 307508-95-8)
- 5,6-Dibromo-3-nitropyridin-2-amine (CAS 868360-22-9)
- 6-Bromo-5-methoxyisoindolin-1-one (CAS 1427360-45-9)
- Sulfur, (2,3-dihydro-2-thioxo-6-benzoxazolyl)pentafluoro-, (OC-6-21)- (CAS 1394319-60-8)
- 1-(4-Chlorophenethyl)-6,7-dimethoxy-2-(3-methylbut-2-en-1-yl)-1,2,3,4-tetrahydroisoquinoline (CAS 63937-77-9)
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- 5-Ethyl-1-(4-fluoro-3-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1239720-61-6)
- 3,5-Difluoropicolinamide (CAS 745784-03-6)
- Insulin Degludec Impurity 25 (CAS CATO-C4X-215725)
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