Nateglinide EP Impurity F CAS 944746-48-9
| CAS No. | 944746-48-9 |
| Molecular Formula | C28H36N2O4 |
| Molecular Weight | 464.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Nateglinide EP Impurity F (CAS 944746-48-9) is a certified pharmaceutical impurity reference standard with the molecular formula C28H36N2O4 and a molecular weight of 464.60 g/mol.
Based on its molecular formula C28H36N2O4, Nateglinide EP Impurity F contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 464.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Nateglinide EP Impurity F meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H36N2O4 |
| Molecular Weight | 464.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Nateglinide Standards
- ent-Nateglinide Acyl-β-D-glucuronide (CAS 1357003-01-0)
- Nateglinide Acyl-β-D-glucuronide (CAS 183996-85-2)
- Nateglinide EP Impurity G (CAS 187728-85-4)
- Nateglinide Impurity 8 (CAS 105746-47-2)
- Nateglinide-d5 (phenyl-d5) (CAS 1227666-13-8)
- Nateglinide Impurity 3 (CAS 491828-09-2)
- Nateglinide EP Impurity B (CAS 105816-05-5)
- Nateglinide (CAS 105816-04-4)
Recommended Standards
- 2-((3-Methoxybenzyl)thio)-3-(4-methoxyphenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 477331-25-2)
- N Desmethyl Ulipristal Acetate D3 (CAS CATO-C4X-191536)
- 1,1'-(Oxybis(4,1-phenylenesulfonyl))dipiperidine (CAS 313493-63-9)
- Methyl 2-3-4-tri-O-benzyl-β-L-thiofucopyranoside (CAS 107802-80-2)
- Rtitrexed Impurity 24 (CAS CATO-C4X-138624)
- Empagliflozin Impurity 124 (CAS CATO-C4X-1065124)
- Flucloxacillin impurity 14 (CAS CATO-C4X-164714)
- Rimegepant Impurity 57 (CAS CATO-C4X-248757)
- 1,3,4,6-Tetrakis-O-(1-oxohexadecyl)- β-D-fructofuranosyl-α-D-glucopyranoside tetrapalmitate (CAS 39024-75-4)
- Methyl 1-Methyl-3-phenylpyrazole-5-carboxylate (CAS 10250-62-1)
- 3-(3-Chlorophenyl)-4-((2-hydroxy-3-methoxybenzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478254-64-7)
- 2’-Methoxy-4’-nitrophenylAcetophenone (CAS 90564-14-0)
- N-(1-(4-fluorophenyl)ethyl)-N-isopropylglycine (CAS 1353959-95-1)
- Insulin Glargine Metabolite M2 (CAS CATO-CPTD788867)
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