2-Chloro-5-methylpyrimidine hydrochloride CAS 94477-14-2
| CAS No. | 94477-14-2 |
| Molecular Formula | C5H5ClN2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-5-methylpyrimidine hydrochloride.
2-Chloro-5-methylpyrimidine hydrochloride (CAS 94477-14-2), molecular formula C5H5ClN2HCl and molecular weight 165.02 g/mol, is a CATO reference standard with documented purity and traceability.
2-Chloro-5-methylpyrimidine hydrochloride (C5H5ClN2HCl) contains a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Chloro-5-methylpyrimidine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H5ClN2 HCl |
| Molecular Weight | 165.02 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- benzyl 4-(5-chloro-1-(2-ethoxy-2-oxoethyl)-6-oxo-1,6-dihydropyridazin-4-yl)piperazine-1-carboxylate (CAS 1000018-18-7)
- 3-[(2-Chloro-4-methylsulfonyl)phenoxy]benzoic acid (CAS 1000018-31-4)
- 6-Chloro-2-[2-(3-[(6-chloro-1-ethylbenz[c,d,]indole-2[1H]-ylidene)ethylidene]-2-phenyl-1-cyclopenten-1-yl)ethenyl]-1-ethylbenz[c,d]indolium tetrafluoroborate (CAS 100012-45-1)
- 3-Chloro-2-fluoro-5-iodobenzoic acid (CAS 1000162-09-3)
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- 2-Chloro-N-(piperidin-4-yl)-6,7-dihydro-5H-cyclopenta-[d]pyrimidin-4-amine hydrochloride (CAS 1000207-51-1)
- 4-chloro-6-(3,3-difluoropyrrolidin-1-yl)pyrimidine (CAS 1000303-40-1)
Recommended Standards
- (1-Ethoxycyclopropyl)(piperazin-1-yl)methanone hydrochloride (CAS 2306271-74-7)
- 3,3-Dimethyl-1-oxo-3,4-dihydro-1H-2-benzopyran-4-carboxylic acid (CAS 255841-48-6)
- 4-(3-Methyl-1H-pyrazol-1-yl)benzaldehyde (CAS 79382-71-1)
- Ethyl 4-([1,1'-biphenyl]-4-yl)-2-(3-chloropropanamido)thiophene-3-carboxylate (CAS 315684-10-7)
- Potassium (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl phosphate dihydrate (CAS 5996-14-5)
- 5-Bromo-N-(4-fluorobenzyl)nicotinamide (CAS 796998-91-9)
- 4-amino-5-(oxan-2-yl)-4H-1,2,4-triazole-3-thiol (CAS 1250977-49-1)
- 5',5''''-Methylenebis(2'-amino-[1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid) (CAS 2378131-12-3)
- H-Glu-Gly-Phe-OH (CAS 42155-93-1)
- Semaglutide impurity 29 (CAS 110990-08-4)
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