1-(4-(Trifluoromethyl)pyrimidin-2-yl)ethan-1-amine CAS 944899-95-0
| CAS No. | 944899-95-0 |
| Molecular Formula | C7H8F3N3 |
| Molecular Weight | 191.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
1-(4-(Trifluoromethyl)pyrimidin-2-yl)ethan-1-amine (CAS 944899-95-0), molecular formula C7H8F3N3 and molecular weight 191.15 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(4-(Trifluoromethyl)pyrimidin-2-yl)ethan-1-amine (C7H8F3N3) is characterized by a nitrile group, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H8F3N3 |
| Molecular Weight | 191.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 2-[6-(Trifluoromethyl)pyridin-3-yl]ethan-1-ol (CAS 1000528-63-1)
- 1-[1-methyl-5-(trifluoromethyl)-1H-pyrrol-2-yl]ethan-1-one (CAS 1068468-94-9)
- 1-Methyl-3-(trifluoromethyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole (CAS 1083224-56-9)
- (6-Methyl-2-(4-(trifluoromethyl)phenyl)imidazo[1,2-a]pyridin-3-yl)methanol (CAS 113265-44-4)
- (R)-1-(2-(trifluoromethyl)pyrimidin-5-yl)ethan-1-amine (CAS 1150263-75-4)
- 3-Oxo-3-(1-(trifluoromethyl)cyclobutyl)propanenitrile (CAS 1188909-23-0)
- 2-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazine (CAS 1196154-97-8)
- alpha-(Trifluoromethyl)-6-methylpyridine-3-methanol (CAS 1226507-25-0)
Recommended Standards
- 1-(2-Aminophenyl)-2,2,2-trifluoroethan-1-ol (CAS 205756-49-6)
- 1-(6-(Trifluoromethyl)pyridazin-3-yl)ethan-1-amine (CAS 2167182-81-0)
- 1-(2,4-Dimethyl-1H-pyrrol-3-yl)-2,2,2-trifluoroethanone (CAS 202286-38-2)
- 1,6-Dimethyl-4-(trifluoromethyl)pyridin-2(1H)-one (CAS 343981-56-6)
- 3-Methylbut-3-en-2-amine hydrochloride (CAS 65296-18-6)
- NSC 61610, >98% (CAS 27111-43-9)
- Benzyl N-[(1S,3R)-rel-3-hydroxycyclopentyl]carbamate (CAS 1932090-03-3)
- N-Desthienylethyl-rotigotine (CAS 78950-82-0)
- 3-[(benzylamino)methyl]benzamide hydrochloride (CAS 1181457-81-7)
- Methyl 2-((2-methoxy-2-oxoethyl)thio)benzoate (CAS 6287-88-3)
- Dimethyl perfluoro-3,6-dioxaoctane-1,8-dioate (CAS 24647-20-9)
- 4-(3-IODO-1H-PYRAZOL-4-YL)PYRIMIDINE (CAS 1111638-50-6)
- Methyl 3-(2-(2-fluorobenzamido)phenoxy)thiophene-2-carboxylate (CAS 900015-01-2)
- Mast Cell Degranulating Peptide (CAS 83856-13-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com