2-(4-Chloropyrimidin-2-yl)ethan-1-amine CAS 944901-23-9
| CAS No. | 944901-23-9 |
| Molecular Formula | C6H8ClN3 |
| Molecular Weight | 157.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(4-Chloropyrimidin-2-yl)ethan-1-amine (CAS 944901-23-9) is a high-purity analytical reference standard with the molecular formula C6H8ClN3 and a molecular weight of 157.60 g/mol.
Based on its molecular formula C6H8ClN3, 2-(4-Chloropyrimidin-2-yl)ethan-1-amine contains a nitrile group, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 157.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H8ClN3 |
| Molecular Weight | 157.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloropyrimidin Standards
- (R)-1-(2-chloropyrimidin-5-yl)ethan-1-amine (CAS 1344616-35-8)
- 2-(2-Chloropyrimidin-4-yl)ethanamine (CAS 1393568-29-0)
- 1-(4-Chloropyrimidin-2-yl)-N-methylmethanamine (CAS 2068150-43-4)
- 1-(5-Chloropyrimidin-2-yl)ethan-1-amine (CAS 944902-32-3)
- 1-(5-Chloropyrimidin-2-yl)-N-methylmethanamine (CAS 944903-19-9)
- 2-(2-Chloropyrimidin-5-yl)ethan-1-amine (CAS 933702-59-1)
- 2-(5-Chloropyrimidin-2-yl)ethan-1-amine (CAS 944900-26-9)
- N-(2-Chloropyrimidin-5-yl)formamide (CAS 56621-85-3)
Recommended Standards
- 1-[(Aminooxy)methyl]-4-chlorobenzene (CAS 5555-51-1)
- 2-(AMinomethyl)-3-chlorophenol (CAS 71712-69-1)
- 1-(6-Chloropyridin-3-yl)ethanol (CAS 23092-75-3)
- 2-(Chloromethyl)-6-methylpyridin-3-ol (CAS 317847-65-7)
- 3-[(2,4-Difluorobenzyl)oxy]pyrrolidinehydrochloride (CAS 1220035-48-2)
- N-Hydroxy-5-((p-tolylsulfinyl)methyl)isoxazole-3-carboxamide (CAS 823220-30-0)
- 1,2,3-Trimethoxy-10-methylacridin-9(10H)-one (CAS 13082-16-1)
- Methyl 2,2,4,4-tetramethyloxazolidine-3-carboxylate (CAS 936493-29-7)
- 6-Methyl-2-(4-propoxyphenyl)quinoline-4-carboxylic acid (CAS 438217-48-2)
- (1-(2,3-Difluorobenzyl)cyclopropyl)methanamine (CAS 1502309-67-2)
- (7-Methoxy-benzo[d]imidazo-[2,1-b]thiazol-2-yl)-methanol (CAS 122830-11-9)
- 2-Methoxy-3-methylbenzonitrile (CAS 53078-68-5)
- 1-(4-(Difluoromethoxy)-2-methylphenyl)ethan-1-one (CAS 1092448-34-4)
- Tirzepatide-d7 Ditrifluoroacetate (CAS CATO-CPTD788698)
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