4-Chloro-2-methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine CAS 944901-74-0

Purity 97%+In StockPharmaceutical Standards
CAS No.944901-74-0
Molecular FormulaC8H10ClN3O
Molecular Weight199.64 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Chloro-2-methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine CAS 944901-74-0 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-2-methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine.

4-Chloro-2-methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (CAS 944901-74-0) is a high-purity analytical reference standard with the molecular formula C8H10ClN3O and a molecular weight of 199.64 g/mol.

The molecular framework of 4-Chloro-2-methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (C8H10ClN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Chloro-2-methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H10ClN3O
Molecular Weight199.64 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl-containing
Nitrogen Atoms3

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