[5-(trifluoromethyl)-1H-1,2,4-triazol-3-yl]methanamine CAS 944905-92-4

Purity 97%+In StockPharmaceutical Standards
CAS No.944905-92-4
Molecular FormulaC4H5F3N4
Molecular Weight166.10 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

[5-(trifluoromethyl)-1H-1,2,4-triazol-3-yl]methanamine CAS 944905-92-4 chemical structure

Description

The occurrence of [5-(trifluoromethyl)-1H-1,2,4-triazol-3-yl]methanamine is closely related to a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies [5-(trifluoromethyl)-1H-1,2,4-triazol-3-yl]methanamine (CAS 944905-92-4), a certified reference material (molecular formula C4H5F3N4, MW 166.10 g/mol) for analytical method development and quality control.

The molecular framework of [5-(trifluoromethyl)-1H-1,2,4-triazol-3-yl]methanamine (C4H5F3N4) is characterized by a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures [5-(trifluoromethyl)-1H-1,2,4-triazol-3-yl]methanamine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC4H5F3N4
Molecular Weight166.10 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1987
Halogen ContentF-containing
Nitrogen Atoms4

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