6-amino-1,3-dimethyl-5-{[2-(pyridin-2-yl)quinolin-4-yl]carbonyl}-1,2,3,4-tetrahydropyrimidine-2,4-dione CAS 945008-17-3
| CAS No. | 945008-17-3 |
| Molecular Formula | C21H17N5O3 |
| Molecular Weight | 387.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-amino-1,3-dimethyl-5-{[2-(pyridin-2-yl)quinolin-4-yl]carbonyl}-1,2,3,4-tetrahydropyrimidine-2,4-dione.
CATO supplies 6-amino-1,3-dimethyl-5-{[2-(pyridin-2-yl)quinolin-4-yl]carbonyl}-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 945008-17-3), a certified reference material (molecular formula C21H17N5O3, MW 387.39 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, 6-amino-1,3-dimethyl-5-{[2-(pyridin-2-yl)quinolin-4-yl]carbonyl}-1,2,3,4-tetrahydropyrimidine-2,4-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 387.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-amino-1,3-dimethyl-5-{[2-(pyridin-2-yl)quinolin-4-yl]carbonyl}-1,2,3,4-tetrahydropyrimidine-2,4-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H17N5O3 |
| Molecular Weight | 387.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 5 |
Related amino Standards
- 3-Amino-N-(4-benzylphenyl)-5-nitro-1H-indazole-1-carboxamide (CAS 1263320-06-4)
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- Ethyl (4-amino-1-benzhydryl-1H-[1,2,3]triazolo[4,5-c]pyridin-6-yl)carbamate (CAS 38359-69-2)
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- 3-Amino-N-(2,4-difluorophenyl)-6-ethyl-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide (CAS 445269-11-4)
- 3-Amino-N-(2,5-difluorophenyl)-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 445268-97-3)
- 3-Amino-N-(3,4-difluorophenyl)-6-ethyl-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide (CAS 445269-03-4)
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Recommended Standards
- 4-Methyl-N-(3-(5-methylbenzo[d]oxazol-2-yl)phenyl)-3-nitrobenzamide (CAS 313667-54-8)
- Ethyl 4-(4-(4-(1H-imidazol-1-yl)benzoyl)-1H-1,2,3-triazol-1-yl)benzoate (CAS 478248-78-1)
- 3-((4-(1-(2-(4-Aminophenyl)-2-oxoethyl)-1H-benzo[d]imidazol-2-yl)-1,2,5-oxadiazol-3-yl)amino)propanenitrile (CAS 798577-91-0)
- Ethyl 5-hydroxy-7-oxo-2,8-diphenyl-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylate (CAS 76360-75-3)
- 2,7-Dibromo-9H-fluorene-9,9-dipropanoic acid (CAS 94257-59-7)
- Tris(ethanolamine)copper(2+) (CAS 53139-76-7)
- 2-Ethynyl-1-fluoro-3-nitrobenzene (CAS 2229510-83-0)
- 5-(Cyclopentyloxy)pyridazin-3(2H)-one (CAS 1346697-83-3)
- Clopidogrel Impurity 78 (CAS CATO-C4X-102978)
- 2-amino-N,N-dimethyl-2-phenylacetamide hydrochloride (CAS 1214036-19-7)
- 4-Chloro-2-(cyclohexyloxy)pyridine (CAS 1346707-01-4)
- Acetylated Penicilloic Acid Disodium Salt (CAS CATO-C3D-263263)
- 3-(2-Chlorobenzyl)quinazolin-4(3H)-one (CAS 82387-82-4)
- Semaglutide Impurity 164 (CAS CATO-C4X-2226164)
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