2-Chloro-5-(methylamino)pyridine-4-carboxylic acid CAS 945737-64-4
| CAS No. | 945737-64-4 |
| Molecular Formula | C7H7ClN2O2 |
| Molecular Weight | 186.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 186.60 g/mol gives 2-Chloro-5-(methylamino)pyridine-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-Chloro-5-(methylamino)pyridine-4-carboxylic acid (CAS 945737-64-4), a certified reference material (molecular formula C7H7ClN2O2, MW 186.60 g/mol) for analytical method development and quality control.
2-Chloro-5-(methylamino)pyridine-4-carboxylic acid (C7H7ClN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-5-(methylamino)pyridine-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H7ClN2O2 |
| Molecular Weight | 186.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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- 2-Chloro-4-ethyl-5-nitropyridine (CAS 101251-13-2)
- (2-Chloro-6-nitrophenyl)methanamine (CAS 101252-73-7)
- 4-Chloro-n',2-dihydroxybenzimidamide (CAS 101252-75-9)
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Recommended Standards
- 2-Chloro-4-methyl-6-nitroaniline (CAS 5465-33-8)
- 2-Chloro-5,6-dimethyl-3-nitropyridine (CAS 65213-96-9)
- 2-CHloro-4-hydroxybenzohydrazide (CAS 219685-79-7)
- 2-Chloro-5-hydrazinylbenzoic acid (CAS 327092-95-5)
- 2-Bromo-4,6-bis(trifluoromethyl)aniline (CAS 243977-18-6)
- 3-Ethylindoline-1-carbonyl chloride (CAS 117086-92-7)
- N-Cyclopropyl-1-(1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carbonyl)piperidine-3-carboxamide hydrochloride (CAS 1160245-30-6)
- (2S)-1-(2-methylpropyl)pyrrolidine-2-carboxylic acid (CAS 1044637-62-8)
- Methyl 6-fluoro-1H-pyrrolo[2,3-b]pyridine-4-carboxylate (CAS 1190321-57-3)
- 1,3-Bis(chloromethoxy)propane (CAS 138418-40-3)
- 2-(tert-Butyl)-5-chloro-3-cyclopropoxypyridine (CAS 1243384-15-7)
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