2-Bromo-3-fluoro-5-nitrophenol CAS 945971-14-2
| CAS No. | 945971-14-2 |
| Molecular Formula | C6H3BrFNO3 |
| Molecular Weight | 236.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Bromo-3-fluoro-5-nitrophenol (CAS 945971-14-2) is a high-purity analytical reference standard with the molecular formula C6H3BrFNO3 and a molecular weight of 236.00 g/mol.
The molecular framework of 2-Bromo-3-fluoro-5-nitrophenol (C6H3BrFNO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H3BrFNO3 |
| Molecular Weight | 236.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 4-Bromo-5-fluoro-2-nitrophenol (CAS 1016234-87-9)
- 2-Bromo-3-fluoro-6-nitrophenol (CAS 103979-08-4)
- 2-bromo-5-fluoro-3-nitro-pyridin-4-amine (CAS 1227958-53-3)
- 4-Bromo-5-fluoro-3-nitropyridin-2-amine (CAS 1360438-55-6)
- 2-Bromo-5-fluoro-4-nitrophenol (CAS 1369139-60-5)
- 3-Bromo-4-fluoro-2-nitrophenol (CAS 1374772-55-0)
- 3-Bromo-2-fluoro-6-nitrophenol (CAS 1804406-89-0)
- 4-Bromo-2-fluoro-3-nitrophenol (CAS 1805031-72-4)
Recommended Standards
- 1-Butyl-3-(trifluoromethyl)pyrazole-5-boronic acid (CAS 2377611-39-5)
- 2-Bromo-4-fluoro-5-nitrophenol (CAS 84478-87-5)
- (1-Isobutyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)boronic acid (CAS 2304633-89-2)
- 2-Bromo-4-fluoro-6-nitrophenol (CAS 320-75-2)
- 3-Methoxycarbonyl-1-(methyl-d3)pyridinium Iodide (CAS 131448-16-3)
- n-Isopropyl-2-((1-oxo-2,3-dihydro-1h-inden-4-yl)oxy)acetamide (CAS 1285583-88-1)
- (4S)-2-(Carboxy(((5-methyl-3-phenylisoxazol-4-yl)carbonyl)amino)methyl)-5,5-dimethylthiazolidine-4-carboxylic Acid (Penicilloic Acids of Oxacillin) (CAS 1642629-95-5)
- 1-Butyl-1-methylpiperidin-1-ium chloride (CAS 845790-13-8)
- N-Acetyl-N'-phenylurea (CAS 102-03-4)
- Ethyl 2-bromo-4-(4-(tert-butyl)phenyl)thiazole-5-carboxylate (CAS 1188153-86-7)
- 4-(3,4-Dimethoxyphenyl)-3-ethyl-1-methyl-1H-pyrazol-5-amine (CAS 957514-04-4)
- 4-Benzyl-1,4-oxazepan-6-ol (CAS 943443-03-6)
- Phosphoric acid, monobutyl ester, potassium salt (CAS 26290-70-0)
- Des-Gln24-Tirzepatide (CAS CATO-CPTD788949)
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