2,2,2-Trifluoro-1-(3'-fluorobiphenyl-4-yl)ethanol CAS 945978-63-2

Purity 97%+In StockPharmaceutical Standards
CAS No.945978-63-2
Molecular FormulaC14H10F4O
Molecular Weight270.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,2,2-Trifluoro-1-(3'-fluorobiphenyl-4-yl)ethanol CAS 945978-63-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,2,2-Trifluoro-1-(3'-fluorobiphenyl-4-yl)ethanol.

2,2,2-Trifluoro-1-(3'-fluorobiphenyl-4-yl)ethanol (CAS 945978-63-2) is a high-purity analytical reference standard with the molecular formula C14H10F4O and a molecular weight of 270.22 g/mol.

The molecular framework of 2,2,2-Trifluoro-1-(3'-fluorobiphenyl-4-yl)ethanol (C14H10F4O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2,2,2-Trifluoro-1-(3'-fluorobiphenyl-4-yl)ethanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H10F4O
Molecular Weight270.22 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing

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