2-hydroxy-5-nitrobenzohydrazide CAS 946-32-7
| CAS No. | 946-32-7 |
| Molecular Formula | C7H7N3O4 |
| Molecular Weight | 197.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-hydroxy-5-nitrobenzohydrazide (C7H7N3O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2-hydroxy-5-nitrobenzohydrazide (CAS 946-32-7), a certified reference material (molecular formula C7H7N3O4, MW 197.15 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7N3O4 |
| Molecular Weight | 197.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 3 |
Related hydroxy Standards
- 2-Hydroxy-3-nitrobenzenecarbohydrazide (CAS 945-22-2)
- 4-hydroxy-6-(trifluoromethyl)pyridine-3-carbaldehyde (CAS 1196146-48-1)
- 2-Hydroxy-2-(4-nitrophenyl)acetic acid (CAS 10098-39-2)
- Methyl 2-hydroxy-6-nitrobenzoate (CAS 1261504-50-0)
- 2-(3-Hydroxy-5-nitrophenyl)acetic acid (CAS 1261746-17-1)
- Methyl 2-hydroxy-4-nitrobenzoate, 97% (CAS 13684-28-1)
- 2-Hydroxy-6-(methoxycarbonyl)isonicotinic acid (CAS 1373959-10-4)
- 4-Hydroxy-6-(methoxycarbonyl)picolinic acid (CAS 1374754-19-4)
Recommended Standards
- 2-Methoxy-5-nitronicotinamide (CAS 60524-16-5)
- 2-Cyclopropyl-5-nitropyrimidine-4,6-diol (CAS 75438-77-6)
- 2-Methyl-3,6-dinitroaniline (CAS 56207-39-7)
- 2-Acetamido-4-nitropyridine 1-oxide (CAS 4487-48-3)
- 2-Ethyl-4-ethynylpyridine (CAS 1215782-60-7)
- Muraglitazar (CAS 331741-94-7)
- Chromium(III) Chromate (CAS 24613-89-6)
- N-(1H-benzo[d]imidazol-2-yl)thiophene-3-carboxamide (CAS 55842-48-3)
- Ganoderic Acid N (CAS 110241-19-5)
- 593-87-3 CHEBI:132481 Guanidine monoacetate Guanidine, acetate (1:1) acetic acid--guanidine (1/1) amino(imino)methanaminium acetate guanidine acetate guanidinium acetate guanidinium monoacetate (CAS 593-87-3)
- All-rac-alfa-Tocopherol EP Impurity B (Mixture of Diastereomers) (CAS CATO-C4X-119515)
- 2-(1-Ethylpiperidin-2-yl)ethan-1-ol (CAS 876488-02-7)
- Quercetin-7-O-glucuronide (CAS 38934-20-2)
- Peptide Impurity 26 (CAS 1350456-66-4)
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