N-[2-(Methylamino)ethyl]methanesulfonamide CAS 946071-33-6
| CAS No. | 946071-33-6 |
| Molecular Formula | C4H12N2O2S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-[2-(Methylamino)ethyl]methanesulfonamide (C4H12N2O2SHCl) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
N-[2-(Methylamino)ethyl]methanesulfonamide (CAS 946071-33-6) is a high-purity analytical reference standard with the molecular formula C4H12N2O2SHCl and a molecular weight of 188.67 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-[2-(Methylamino)ethyl]methanesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H12N2O2S HCl |
| Molecular Weight | 188.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | -1.0 |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- 4-(Methylamino)phenyl furan-2-carboxylate (CAS 100063-33-0)
- 2-(methylamino)-6,7-dihydro-3H-purin-6-one (CAS 10030-78-1)
- 6-(Methylamino)pyridine-3-boronic Acid Pinacol Ester (CAS 1005009-98-2)
- 2-(Methylamino)cyclopentan-1-ol (CAS 100524-01-4)
- 2-(Methylamino)ethane-1-thiol (CAS 10061-40-2)
- 1-(2-(Methylamino)-2-oxoethyl)-1H-pyrazole-3-carboxylic acid (CAS 1006463-30-4)
- Ethyl 4-((methylamino)methyl)benzoate hydrochloride (CAS 1007870-76-9)
- 2-methyl-2-(methylamino)-1-phenyl-propan-1-ol (CAS 10079-55-7)
Recommended Standards
- 1-Methylimidazo[1,5-a]pyridine-6-carboxylic acid (CAS 1260797-04-3)
- 3-Aminopyridine-2-sulfonic acid (CAS 54247-51-7)
- 5-(3H-Indol-2-yl)-1,3,4-oxadiazol-2(3H)-one (CAS 88458-43-9)
- 4-Fluorophenyl methyl(phenyl)carbamate (CAS 526190-34-1)
- N-(Trimethylsilylmethyl)benzylamine (CAS 53215-95-5)
- Tert-butyl 4-(1H-indazol-1-yl)piperidine-1-carboxylate (CAS 2386361-81-3)
- 4-[Hydroxy(4-methoxyphenyl)methyl]benzonitrile (CAS 174813-84-4)
- 4-((1,7-Naphthyridin-8-yl)amino)-4-oxobutanoic acid (CAS 396682-90-9)
- (3R,4S,5R,6R)-6-(Acetoxymethyl)-5-(((2R,3R,4S,5R,6R)-3,4-diacetoxy-6-(acetoxymethyl)-5-(((2R,3R,4S,5R,6R)-3,4,5-triacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2,3,4-triyl triacetate (CAS 76821-26-6)
- Semaglutide Impurity 4 (CAS CATO-C4X-22264)
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