3-(2-Fluorophenyl)-5-(1-(thiophen-2-ylsulfonyl)piperidin-4-yl)-1,2,4-oxadiazole CAS 946293-96-5
| CAS No. | 946293-96-5 |
| Molecular Formula | C17H16FN3O3S2 |
| Molecular Weight | 393.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(2-Fluorophenyl)-5-(1-(thiophen-2-ylsulfonyl)piperidin-4-yl)-1,2,4-oxadiazole is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-(2-Fluorophenyl)-5-(1-(thiophen-2-ylsulfonyl)piperidin-4-yl)-1,2,4-oxadiazole (CAS 946293-96-5), a certified reference material (molecular formula C17H16FN3O3S2, MW 393.46 g/mol) for analytical method development and quality control.
Structurally, 3-(2-Fluorophenyl)-5-(1-(thiophen-2-ylsulfonyl)piperidin-4-yl)-1,2,4-oxadiazole (C17H16FN3O3S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 393.46 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H16FN3O3S2 |
| Molecular Weight | 393.46 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Fluorophenyl Standards
- 8-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)-[1,2,4]triazolo[4,3-a]pyridine-3(2H)-thione (CAS 1707586-26-2)
- 1-(4-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidin-1-yl)-2-(3-methylphenyl)ethan-1-one (CAS 1775402-83-9)
- 2-(4,4-Bis(4-fluorophenyl)butyl)-1,2,3,4-tetrahydroisoquinolin-8-ol (CAS 827310-59-8)
- 4-{4-[Bis(4-fluorophenyl)methyl]piperazin-1-ylmethyl}phenylamine 914349-63-6 C24H25F2N3 W9459 (CAS 914349-63-6)
- 2-((3-(3-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)-N-(o-tolyl)acetamide (CAS 852374-55-1)
- N-[(4-Fluorophenyl)methyl]-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide (CAS 1105206-96-9)
- N-(4-Fluorophenyl)-2-[2-oxo-5-(piperidine-1-sulfonyl)-1,2-dihydropyridin-1-yl]acetamide (CAS 1251631-02-3)
- 4-(4-(4-Fluorophenyl)-2-(4-(methylsulfonyl)phenyl)-1H-imidazol-5-yl)pyridine (CAS 152121-46-5)
Recommended Standards
- 3-(2,5-Dioxopyrrolidin-1-yl)-N-(3,5,7-trimethylbenzo[d]thiazol-2(3H)-ylidene)benzamide (CAS 868369-91-9)
- 3-{[(9h-fluoren-9-ylmethoxy)carbonyl]amino}-3-(thiophen-2-yl)propanoic acid (CAS 282525-12-6)
- 2-[(2-Benzyl-3-oxo-2,3-dihydro-1H-isoindol-1-yl)sulfanyl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide (CAS 866008-71-1)
- 3-Tosyloxy-4-benzyloxybenzyl Cyanide (CAS 65615-26-1)
- Methyl 5-chloro-4-[(hydroxyimino)methyl]-1-phenyl-1H-pyrazole-3-carboxylate (CAS 320423-32-3)
- 2-Pyridin-3-ylquinoline-4-carbonyl chloridehydrochloride (CAS 1332529-39-1)
- 3-(1,2,2-Trimethylhydrazinyl)propanoic acid (CAS 153050-92-1)
- Sodium 2-methoxyethanesulfonate (CAS 77281-03-9)
- (2,6-Diaminopyridin-3-yl)(phenyl)methanone (CAS 157924-28-2)
- 1-(1-Methyl-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-2-yl)piperidine-4-carboxylic acid (CAS 1707566-39-9)
- 168206-23-3 4-[4-(2-Carboxyphenyl)-7-(diethylamino)-2H-1-benzopyran-2-ylidene]-N,N-dimethylcyclohexa-2,5-dien-1-iminium perchlorate DTXSID20584079 (CAS 168206-23-3)
- 5-Methyl-2-[3-(trifluoromethyl)phenyl]-1H-imidazole-4-carboxylic Acid (CAS 1153734-86-1)
- 2-[4-(2-Fluoro-benzyloxy)-phenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (CAS 2246642-41-9)
- D-β-Asp15-Tirzepatide (CAS CATO-CPTD788930)
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