2-(5-Oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-3-yl)-N-(2,3,4-trifluorophenyl)acetamide CAS 946341-95-3
| CAS No. | 946341-95-3 |
| Molecular Formula | C14H10F3N3O2S |
| Molecular Weight | 341.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(5-Oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-3-yl)-N-(2,3,4-trifluorophenyl)acetamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(5-Oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-3-yl)-N-(2,3,4-trifluorophenyl)acetamide (CAS 946341-95-3), molecular formula C14H10F3N3O2S and molecular weight 341.31 g/mol, is a CATO reference standard with documented purity and traceability.
2-(5-Oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-3-yl)-N-(2,3,4-trifluorophenyl)acetamide (C14H10F3N3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(5-Oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-3-yl)-N-(2,3,4-trifluorophenyl)acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H10F3N3O2S |
| Molecular Weight | 341.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Oxo Standards
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- n-(2,3-Dihydro-1h-inden-5-yl)-2-(2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetamide (CAS 791086-46-9)
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Recommended Standards
- 2-(3-Methyl-6-(thiophen-2-yl)-4-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 937605-82-8)
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- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)malonic acid (CAS 296261-32-0)
- 3-(3-(Benzo[d][1,3]dioxol-5-yloxy)-2-oxopyrrolidin-1-yl)benzoic acid (CAS 649773-85-3)
- 3,4-Dichloro-1,6-dimethylpyridin-2(1H)-one (CAS 1706432-20-3)
- 3-Ethynylbenzene-1-sulfonyl fluoride (CAS 2138286-81-2)
- 1-(4-Nitrophenyl)-3-propyl-1H-pyrazol-5-ol (CAS 418804-55-4)
- Methyl 6-ethoxypicolinate (CAS 55980-65-9)
- 2-(Aminomethyl)oxazole-4-carboxylic acid (CAS 1314974-14-5)
- 5-Bromo-2-(cyanomethyl)-6-fluorobenzimidazole (CAS 1514433-81-8)
- N-(4H-1,2,4-Triazol-4-yl)-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxamide (CAS 717872-62-3)
- 6-Chloro-7-methoxy-1H-indazole (CAS 1427369-59-2)
- Rivaroxaban Impurity 23 (CAS 26020-48-4)
- [Formaldehyde Schiff-base]-Semaglutide Impurity 136 X TFA Salt (CAS CATO-C4X-2226136)
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