5-Methyl-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)isoxazole-3-carboxamide CAS 946357-12-6
| CAS No. | 946357-12-6 |
| Molecular Formula | C11H8N4O3S |
| Molecular Weight | 276.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Methyl-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)isoxazole-3-carboxamide (CAS 946357-12-6) is a high-purity analytical reference standard with the molecular formula C11H8N4O3S and a molecular weight of 276.27 g/mol.
The molecular framework of 5-Methyl-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)isoxazole-3-carboxamide (C11H8N4O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Methyl-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)isoxazole-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8N4O3S |
| Molecular Weight | 276.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Recommended Standards
- 3-Nitro-4-(pyridin-2-ylthio)benzoic acid (CAS 219930-74-2)
- 5-Nitro-2-(pyridin-2-ylthio)benzoic acid (CAS 392726-23-7)
- 3-Methyl-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)isoxazole-5-carboxamide (CAS 952964-72-6)
- Bis(2-nitrophenyl) Sulfide (CAS 22100-66-9)
- 2-[2-(2-Chlorophenoxy)ethyl]piperidinehydrochloride (CAS 1220019-09-9)
- (4E)-4-{[(3-chlorophenyl)amino]methylidene}-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carbonitrile (CAS 338415-20-6)
- 1-(3-Iodo-6-methoxy-1H-indazol-1-yl)ethan-1-one (CAS 1337880-96-2)
- 6-(4-(2-Methoxyphenyl)piperazin-1-yl)-9H-purine (CAS 47281-43-6)
- 2-(Benzylamino)-2-phenylacetic acid (CAS 1859-51-4)
- 3-(4-Chlorobutyl)-1H-indole-5-carboxamide (CAS 173150-58-8)
- 6-Bromo-5-(difluoromethyl)-3-methoxypicolinaldehyde (CAS 1805246-61-0)
- Ethyl 5-bromo-1-(pyrimidin-2-yl)-1H-pyrazole-4-carboxylate (CAS 1269292-57-0)
- MEthyl 3-benzenesulfonamidopropanoate (CAS 91819-18-0)
- Semaglutide Impurity 5 (CAS 23406-82-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com