2-((1-Cyclohexyl-1H-imidazol-2-yl)thio)-N-(3,5-dimethylphenyl)acetamide CAS 946367-60-8
| CAS No. | 946367-60-8 |
| Molecular Formula | C19H25N3OS |
| Molecular Weight | 343.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-((1-Cyclohexyl-1H-imidazol-2-yl)thio)-N-(3,5-dimethylphenyl)acetamide (C19H25N3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
2-((1-Cyclohexyl-1H-imidazol-2-yl)thio)-N-(3,5-dimethylphenyl)acetamide (CAS 946367-60-8) is a high-purity analytical reference standard with the molecular formula C19H25N3OS and a molecular weight of 343.49 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H25N3OS |
| Molecular Weight | 343.49 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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