6-(4-Bromophenyl)-2-chloronicotinonitrile CAS 946601-95-2
| CAS No. | 946601-95-2 |
| Molecular Formula | C12H6BrClN2 |
| Molecular Weight | 293.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 6-(4-Bromophenyl)-2-chloronicotinonitrile (C12H6BrClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 293.55 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
6-(4-Bromophenyl)-2-chloronicotinonitrile (CAS 946601-95-2) is a high-purity analytical reference standard with the molecular formula C12H6BrClN2 and a molecular weight of 293.55 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-(4-Bromophenyl)-2-chloronicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H6BrClN2 |
| Molecular Weight | 293.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromophenyl Standards
- 4-(4-Bromophenyl)-2-chloronicotinonitrile (CAS 1225658-71-8)
- 6-(3-Bromophenyl)-2-chloropyridine-3-carbonitrile (CAS 147426-93-5)
- (2E)-1-(3-Bromophenyl)-3-(thiophen-2-yl)prop-2-en-1-one (CAS 1001166-29-5)
- 2-((3-Bromophenyl)thio)benzaldehyde (CAS 139009-33-9)
- (2E)-1-(4-Bromophenyl)-3-(thiophen-2-yl)prop-2-en-1-one (CAS 2910-79-4)
- 2-(4-Bromophenyl)-5-methyl-4,5,6,7-tetrahydrooxazolo[4,5-c]pyridine (CAS 1017781-96-2)
- 1-(4-Bromophenyl)-3-(propan-2-yl)-1h-pyrazole-4-carbaldehyde (CAS 1152504-95-4)
- (3-Bromophenyl)(2-methoxyphenyl)methanol (CAS 1183724-23-3)
Recommended Standards
- 5-Chloro-3-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile (CAS 2923539-85-7)
- 2,2,2-Trichloroethyl 2-methyl-4,5-dihydro-1H-imidazole-1-sulfonate (CAS 1185733-66-7)
- 4-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one (CAS 2818961-68-9)
- Prasugrel Impurity 10 (CAS 1373350-58-3)
- 5-Ethoxy-3-(methylthio)pyridin-2-amine (CAS 2794196-94-2)
- (3-Cyano-5-cyclopropylphenyl)boronic acid (CAS 2225178-19-6)
- (R)-2-((((Benzyloxy)carbonyl)amino)methyl)-4-methylpentanoic acid (CAS 132606-01-0)
- 3-fluoro-7-methyl-imidazo[1,2-a]pyridine-2-carboxylic acid (CAS 696632-07-2)
- Lefamulinum Impurity 26 (CAS CATO-C4X-304726)
- 4-(Aminomethyl)-1-(2,6-difluorobenzyl)pyrrolidin-2-one hydrochloride (CAS 1177296-22-8)
- 4-oxo-4-(1H-pyrrol-2-yl)butanoic acid (CAS 71739-65-6)
- 2,3-Bis(4-methoxyphenyl)-5-(trifluoromethyl)pyridine (CAS 1400872-27-6)
- Adenosine 5'-diphosphate bis(cyclohexylammonium) salt (CAS 102029-87-8)
- Semaglutide impurity 23 (CAS CATO-C4X-222623)
Why CATO?
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