4-(2-Isopropylphenoxy)-2-(trifluoromethyl)aniline CAS 946663-09-8
| CAS No. | 946663-09-8 |
| Molecular Formula | C16H16F3NO |
| Molecular Weight | 295.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-(2-Isopropylphenoxy)-2-(trifluoromethyl)aniline (CAS 946663-09-8) is a high-purity analytical reference standard with the molecular formula C16H16F3NO and a molecular weight of 295.30 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-(2-Isopropylphenoxy)-2-(trifluoromethyl)aniline is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 295.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H16F3NO |
| Molecular Weight | 295.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Isopropylphenoxy Standards
- 2-(2-Isopropylphenoxy)-5-(trifluoromethyl)aniline (CAS 946773-22-4)
- 2-(3-Isopropylphenoxy)-5-(trifluoromethyl)aniline (CAS 946728-08-1)
- 2-(4-Isopropylphenoxy)-5-(trifluoromethyl)aniline (CAS 946682-76-4)
- 4-(2-Isopropylphenoxy)-3-(trifluoromethyl)aniline (CAS 946740-58-5)
- 4-(3-Isopropylphenoxy)-2-(trifluoromethyl)aniline (CAS 946663-20-3)
- 4-(3-Isopropylphenoxy)-3-(trifluoromethyl)aniline (CAS 946697-67-2)
- 4-(4-Isopropylphenoxy)-2-(trifluoromethyl)aniline (CAS 946784-75-4)
- 4-(4-Isopropylphenoxy)-3-(trifluoromethyl)aniline (CAS 946697-76-3)
Recommended Standards
- 4-(2-Furyl)-5-[2-(4-methoxyphenyl)diazenyl]-2-pyrimidinamine (CAS 338414-27-0)
- 4-(1,4-Diazepan-1-yl)-2-(trifluoromethyl)quinoline (CAS 401566-43-6)
- 3-Phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine (CAS 83891-03-6)
- 3'-(Isopropylamino)-5'-(trifluoromethyl)-[1,1'-biphenyl]-2-ol (CAS 769168-11-8)
- 3-Oxo-1-(3-(trifluoromethoxy)phenyl)cyclobutanecarbonitrile (CAS 1432050-58-2)
- Z-Pro-Pro-OH (CAS 7360-23-8)
- 2-(Piperidin-2-yl)-4-(pyridin-2-yl)thiazole (CAS 1282816-13-0)
- 3-Methyl-5-phenylpent-2-enenitrile (CAS 93893-89-1)
- 5-pentyl-1H-pyrazole-3-carboxylic acid (CAS 89967-38-4)
- 3-Amino-1-propyl-1H-pyrazole-4-carbonitrile (CAS 261629-02-1)
- 6-Bromo-2-methyl-1-(2-oxopropyl)quinolin-4(1H)-one (CAS 1208829-11-1)
- 2-Chloro-4-formylbenzoic Acid (CAS 1289063-25-7)
- 1,14-Dibromo-3,6,9,12-tetraoxatetradecane (CAS 57602-02-5)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
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