4-Methyl-2-[2-(4-morpholinyl)ethoxy]phenylamine CAS 946683-29-0
| CAS No. | 946683-29-0 |
| Molecular Formula | C13H20N2O2 |
| Molecular Weight | 236.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Methyl-2-[2-(4-morpholinyl)ethoxy]phenylamine (C13H20N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
4-Methyl-2-[2-(4-morpholinyl)ethoxy]phenylamine (CAS 946683-29-0) is a high-purity analytical reference standard with the molecular formula C13H20N2O2 and a molecular weight of 236.31 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Methyl-2-[2-(4-morpholinyl)ethoxy]phenylamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H20N2O2 |
| Molecular Weight | 236.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 4-[3-(4-Morpholinyl)propoxy]benzenamine (CAS 100800-40-6)
- 5-Methyl-2-[2-(4-morpholinyl)ethoxy]phenylamine (CAS 946715-66-8)
- 4-(4-Morpholinyl)-3-nitrobenzaldehyde (CAS 300541-91-7)
- 4-Morpholinyl(4-nitrophenyl)methanone (CAS 5397-76-2)
- {2-[2-(4-Morpholinyl)ethoxy]-3-pyridinyl}methanamine (CAS 1894599-25-7)
- 2-[2-(4-Morpholinyl)ethoxy]benzaldehyde (CAS 68997-45-5)
- 3-(3-Oxo-4-morpholinyl)benzeneacetic acid (CAS 1203546-10-4)
- 4-(3-Oxo-4-morpholinyl)benzeneacetic acid (CAS 742073-23-0)
Recommended Standards
- 4-Hydroxy Stiripentol (CAS 58344-42-6)
- 5-(2-Methoxypropan-2-yl)thiazole-2-sulfonamide (CAS 2143028-21-9)
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- 4-[3-(2-methoxyethoxy)azetidin-1-yl]-3-methylaniline (CAS 344405-78-3)
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- 3-Methoxy Dopamine-d4 Hydrochloride (CAS 1216788-76-9)
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- Atrasentan Impurity 43 (CAS 223139-35-3)
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