5-Bromo-2-(2-fluorophenoxy)aniline CAS 946700-02-3

Purity 97%+In StockPharmaceutical Standards
CAS No.946700-02-3
Molecular FormulaC12H9BrFNO
Molecular Weight282.11 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Bromo-2-(2-fluorophenoxy)aniline CAS 946700-02-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 282.11 g/mol gives 5-Bromo-2-(2-fluorophenoxy)aniline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-Bromo-2-(2-fluorophenoxy)aniline (CAS 946700-02-3) is a high-purity analytical reference standard with the molecular formula C12H9BrFNO and a molecular weight of 282.11 g/mol.

5-Bromo-2-(2-fluorophenoxy)aniline (C12H9BrFNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Bromo-2-(2-fluorophenoxy)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H9BrFNO
Molecular Weight282.11 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF/Br-containing
Nitrogen Atoms1

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