4-[2-(1-Piperidinyl)ethoxy]-2-(trifluoromethyl)-phenylamine CAS 946741-14-6
| CAS No. | 946741-14-6 |
| Molecular Formula | C14H19F3N2O |
| Molecular Weight | 288.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-[2-(1-Piperidinyl)ethoxy]-2-(trifluoromethyl)-phenylamine (CAS 946741-14-6), a certified reference material (molecular formula C14H19F3N2O, MW 288.31 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-[2-(1-Piperidinyl)ethoxy]-2-(trifluoromethyl)-phenylamine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 288.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 4-[2-(1-Piperidinyl)ethoxy]-2-(trifluoromethyl)-phenylamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H19F3N2O |
| Molecular Weight | 288.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Piperidinyl Standards
- 2-[2-(1-Piperidinyl)ethoxy]-5-(trifluoromethyl)-aniline (CAS 937596-92-4)
- 5-(2-Ethyl-1-piperidinyl)-2-(methylsulfonyl)-phenylamine (CAS 1220021-46-4)
- [5-(1-Boc-4-piperidinyl)-1H-1,2,4-triazol-3-yl]methanamine (CAS 1546114-32-2)
- 4-(2-Ethyl-1-piperidinyl)-3-nitrobenzoic acid (CAS 1094563-70-8)
- 2-[2-(1-Methyl-2-piperidinyl)ethoxy]-3-phenylpropylamine (CAS 883531-30-4)
- 2-(2-Ethyl-1-piperidinyl)-5-(trifluoromethyl)-phenylamine (CAS 946669-38-1)
- 2-(1-Boc-4-piperidinyl)benzoic Acid (CAS 170838-26-3)
- 1-(4-Piperidinyl)-2-(trifluoromethyl)-1H-benzimidazole (CAS 742076-06-8)
Recommended Standards
- 4,4'-Di(4H-1,2,4-triazol-4-yl)-1,1'-biphenyl (CAS 2057437-56-4)
- 6-(3-(Pyridin-2-yl)-1H-pyrazol-4-yl)quinazolin-4-amine (CAS 746667-28-7)
- 3,4-Diphenyl-[1,2,4]triazolo[5,1-c][1,2,4]triazin-7-amine (CAS 61033-31-6)
- calciumtetrachloropalladate(2-) (CAS 84803-42-9)
- 2-(3-(Methylamino)propyl)isoindoline-1,3-dione (CAS 861199-60-2)
- Methyl 6-fluoro-1H-pyrrolo[3,2-c]pyridine-3-carboxylate (CAS 2231674-12-5)
- 2-(tert-Butylamino)-4-isopropyl-1-methyl-1H-imidazol-5(4H)-one (CAS 787541-53-1)
- 1-(3,4-Difluorophenyl)-3-(4-((6,7-dimethoxyquinolin-3-yl)oxy)-2-fluorophenyl)urea (CAS 1956311-09-3)
- Avibactam Impurity 81 (CAS CATO-C4X-134881)
- Nerandomilast impurity 11 (CAS CATO-C4X-347311)
- 7-Bromo-4-fluoroindolin-2-one (CAS 1260903-29-4)
- 6-(4-Methoxyphenyl)-5-(methylsulfonyl)pyridazin-3(2H)-one (CAS 1713588-48-7)
- Zoloperone (CAS 52867-74-0)
- (DTyr27,36,DThr32)-Neuropeptide Y (27-36) (CAS 163887-48-7)
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