5-Chloro-2-(2-ethoxyethoxy)aniline CAS 946772-83-4
| CAS No. | 946772-83-4 |
| Molecular Formula | C10H14ClNO2 |
| Molecular Weight | 215.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-2-(2-ethoxyethoxy)aniline (CAS 946772-83-4), molecular formula C10H14ClNO2 and molecular weight 215.68 g/mol, is a CATO reference standard with documented purity and traceability.
5-Chloro-2-(2-ethoxyethoxy)aniline (C10H14ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-2-(2-ethoxyethoxy)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14ClNO2 |
| Molecular Weight | 215.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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- 4-chloro-N-(2,2-dimethoxyethyl)aniline (CAS 111318-21-9)
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Recommended Standards
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- 4-[2-(3-CHlorophenyl)vinyl]pyridine (CAS 31428-94-1)
- Levocetrizine Imine Impurity (CAS 2362-79-0)
- 4-Chloro-2-iodobenzaldehyde (CAS 132901-37-2)
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- 2,2,2-Trifluoro-1-(3'-methyl-[1,1'-biphenyl]-4-yl)ethan-1-one (CAS 1443306-99-7)
- 5-(bromomethyl)pyridin-2-amine hydrobromide (CAS 1384972-87-5)
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- 3-((Tert-butoxycarbonyl)amino)-3-cyclobutylpropanoic acid (CAS 903094-78-0)
- His-Cyclic-Semaglutide (CAS CATO-C4X-2226182)
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