Methyl 2-{4-[4-amino-3-(trifluoromethyl)phenoxy]-phenyl}acetate CAS 946784-78-7
| CAS No. | 946784-78-7 |
| Molecular Formula | C16H14F3NO3 |
| Molecular Weight | 325.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Methyl 2-{4-[4-amino-3-(trifluoromethyl)phenoxy]-phenyl}acetate (CAS 946784-78-7), molecular formula C16H14F3NO3 and molecular weight 325.28 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Methyl 2-{4-[4-amino-3-(trifluoromethyl)phenoxy]-phenyl}acetate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 325.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Methyl 2-{4-[4-amino-3-(trifluoromethyl)phenoxy]-phenyl}acetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H14F3NO3 |
| Molecular Weight | 325.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
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Recommended Standards
- N-(2,5-Dimethoxyphenyl)-4-(trifluoromethyl)benzamide (CAS 723757-68-4)
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- Methyl 2-(5-(4-nitrophenyl)-1,3,4-oxadiazol-2-yl)benzoate (CAS 56894-43-0)
- N-phenyl-N-(3-(trifluoromethoxy)benzyl)glycine (CAS 2514942-07-3)
- Propane-1-sulfinamide (CAS 871939-84-3)
- 3,3-Dimethylindoline-5-carbonitrile (CAS 1158745-60-8)
- N-(piperidin-3-ylmethyl)-2-(thiophen-2-yl)acetamide hydrochloride (CAS 1581670-45-2)
- (3,5-Difluorophenyl)(2-(morpholinomethyl)phenyl)methanone (CAS 898751-21-8)
- 7-Fluoro-4-methoxybenzo[d]thiazol-2-amine hydrobromide (CAS 2415163-45-8)
- (1-Isopropyl-1H-pyrazol-3-yl)boronic acid (CAS 2246897-54-9)
- 2-(2-Methoxyethyl) 4-methyl 5-amino-3-methylthiophene-2,4-dicarboxylate (CAS 670271-10-0)
- 1-tert-Butyl 3-methyl 2-((5-bromopyridin-2-yl)methyl)malonate (CAS 656801-27-3)
- 4-(n-Methyl-2-(4-oxothiazolidin-3-yl)acetamido)butanoic acid (CAS 1099068-75-3)
- Semaglutide impurity 272 (CAS CATO-C4X-2226272)
Why CATO?
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