4-Methyl-3-(trifluoromethyl)phenylboronic Acid CAS 947533-94-0
| CAS No. | 947533-94-0 |
| Molecular Formula | C8H8BF3O2 |
| Molecular Weight | 203.95 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Methyl-3-(trifluoromethyl)phenylboronic Acid.
4-Methyl-3-(trifluoromethyl)phenylboronic Acid (CAS 947533-94-0), molecular formula C8H8BF3O2 and molecular weight 203.95 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Methyl-3-(trifluoromethyl)phenylboronic Acid (C8H8BF3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8BF3O2 |
| Molecular Weight | 203.95 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Methyl Standards
- (3-Methyl-2-(trifluoromethyl)phenyl)boronic acid (CAS 1383576-04-2)
- (5-Methyl-2-(trifluoromethyl)phenyl)boronic acid (CAS 1437787-70-6)
- (2-Methyl-3-(trifluoromethyl)phenyl)boronic acid (CAS 947533-86-0)
- (2-Methyl-4-(trifluoromethyl)phenyl)boronic acid (CAS 957034-45-6)
- (2-Methyl-5-(trifluoromethyl)phenyl)boronic acid (CAS 947533-96-2)
- (3-Methyl-5-(trifluoromethyl)phenyl)boronic acid (CAS 850411-13-1)
- {[3-(trifluoromethyl)phenyl]methyl}boronic acid (CAS 21948-55-0)
- 3,5-Bis(trifluoromethyl)-1H-pyrazole (CAS 14704-41-7)
Recommended Standards
- 13966-26-2 Lead, isotope of mass 204 DTXSID00161145 (CAS 13966-26-2)
- 2-Bromo-5-nitropyrazine (CAS 117103-53-4)
- 2-Bromo-5-nitropyrimidine (CAS 1210824-80-8)
- 5-Bromo-2-nitropyrimidine (CAS 1349140-68-6)
- 2',3',4',9'-Tetrahydrospiro[cyclobutane-1,1'-pyrido[3,4-b]indole] (CAS 1956332-31-2)
- N,N-Dimethyl-1-(5-(trifluoromethyl)-pyridin-2-yl)piperidin-4-amine (CAS 1774898-15-5)
- 4-(2-Aminoacetamido)butanoic acid (CAS 32595-49-6)
- 4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-benzylbutanoic acid (CAS 282525-01-3)
- 2-(3-Methylisothiazol-4-yl)acetic acid (CAS 10284-36-3)
- 1-Phenylbut-3-yn-1-amine (CAS 82745-22-0)
- 4-Bromo-n-methyl-n-[(2-methylphenyl)methyl]-1h-pyrrole-2-carboxamide (CAS 1062045-11-7)
- (3-Aminoazetidin-1-yl)(p-tolyl)methanone (CAS 1340352-82-0)
- Methyl 6-amino-5-hydroxybenzofuran-2-carboxylate (CAS 155587-71-6)
- Semaglutide impurity 36 (CAS CATO-C4X-222636)
Why CATO?
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