5-(3,5-Dichlorophenyl)pyrimidin-2-amine CAS 947592-73-6
| CAS No. | 947592-73-6 |
| Molecular Formula | C10H7Cl2N3 |
| Molecular Weight | 240.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-(3,5-Dichlorophenyl)pyrimidin-2-amine (C10H7Cl2N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
5-(3,5-Dichlorophenyl)pyrimidin-2-amine (CAS 947592-73-6), molecular formula C10H7Cl2N3 and molecular weight 240.09 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(3,5-Dichlorophenyl)pyrimidin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7Cl2N3 |
| Molecular Weight | 240.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichlorophenyl Standards
- 5-(2,6-Dichlorophenyl)pyrimidin-2-amine (CAS 1111102-00-1)
- 5-(2,5-Dichlorophenyl)pyrimidin-2-amine (CAS 1111104-96-1)
- 5-(3,4-Dichlorophenyl)pyridin-2(1H)-one (CAS 1111109-41-1)
- 5-(2,3-Dichlorophenyl)pyrimidin-2-amine (CAS 1111111-90-0)
- 2-(2,3-Dichlorophenyl)pyrimidin-4-amine (CAS 1249790-94-0)
- 2-(2,4-Dichlorophenyl)pyrimidin-4-amine (CAS 1250544-45-6)
- 6-(2,4-Dichlorophenyl)pyrimidin-4-amine (CAS 1250580-15-4)
- 2-(3,5-Dichlorophenyl)pyrimidin-4-amine (CAS 1250614-91-5)
Recommended Standards
- 5-(2,4-Dichlorophenyl)-1H-pyrrole-2-carbaldehyde (CAS 708288-96-4)
- 5,6-Dichloro-N-phenylpyrimidin-4-amine (CAS 61810-05-7)
- 4-Chloro-N-(3-chlorophenyl)pyrimidin-2-amine (CAS 950752-52-0)
- 5-CHloro-2-(3-chlorophenoxy)pyridine (CAS 28373-53-7)
- 2-Bromo-4-(difluoromethyl)-3-methoxy-6-(trifluoromethyl)pyridine (CAS 1805424-69-4)
- N-Desmethyl N-Nitroso Topotecan (CAS CATO-C4X-17692)
- N-(4-methylbenzyl)-1-(1,3,5-trimethyl-1H-pyrazol-4-yl)methanamine (CAS 1152936-31-6)
- 5-Bromo-1-(2-((tert-butyldimethylsilyl)oxy)ethyl)-1H-benzo[d]imidazole (CAS 1704067-43-5)
- FLAVANONE HYDRAZONE (CAS 1692-46-2)
- Dapagliflozin Impurity 191 (CAS 1616259-44-9)
- 3-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid (CAS 3734-24-5)
- 3-(Isobutylthio)-5,6-diphenyl-1,2,4-triazine (CAS 353479-43-3)
- 1-(2-Aminoethyl)pyrrolidin-2-one oxalate (CAS 1392113-56-2)
- Peptide YY (human) trifluoroacetate salt (CAS 118997-30-1)
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