Cefuroxime Sodium EP Impurity H(Cefuroxime Axetil EP Impurity E) CAS 947723-87-7
| CAS No. | 947723-87-7 |
| Molecular Formula | C15H13N3O6S |
| Molecular Weight | 363.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Cefuroxime Sodium EP Impurity H(Cefuroxime Axetil EP Impurity E) is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 363.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Cefuroxime Sodium EP Impurity H(Cefuroxime Axetil EP Impurity E) (CAS 947723-87-7) is a certified pharmaceutical impurity reference standard with the molecular formula C15H13N3O6S and a molecular weight of 363.35 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H13N3O6S |
| Molecular Weight | 363.35 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Cefuroxime Standards
- (E)-Cefuroxime Sodium Impurity 43 (CAS CATO-C4X-124543)
- Cefuroxime Impurity 79 (CAS CATO-C4X-124579)
- Cefuroxime Sodium EP Impurity C (CAS 69822-88-4)
- Cefuroxime Impurity 60 (CAS CATO-C4X-124560)
- Cefuroxime Impurity 63 (CAS CATO-C4X-124563)
- Cefuroxime Axetil Impurity 6 (CAS CATO-C4X-14366)
- Cefuroxime Axetil Impurity 15 (CAS 2704612-10-0)
- Cefuroxime Impurity 62 (CAS CATO-C4X-124562)
Recommended Standards
- 1-Oxo-2-(4-phenoxyphenyl)-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole-7-carboxylic acid (CAS 1005151-01-8)
- Ethyl 2-((4-ethyl-5-(1-methyl-5-(trifluoromethyl)-1h-pyrazol-3-yl)-4h-1,2,4-triazol-3-yl)thio)acetate (CAS 1005680-56-7)
- Methyl 4-{4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl}benzenecarboxylate (CAS 321430-12-0)
- Ethyl 2-(4-(difluoromethyl)-6-(1,3-dimethyl-1H-pyrazol-4-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate (CAS 1052634-25-9)
- Posaconazole Impurity 200 (CAS CATO-C4X-1208200)
- Finasteride Impurity 27 (CAS 1329611-51-9)
- Upacicalcet Sodium Impurity 2 (CAS CATO-C4X-33922)
- Fmoc-N-Me-Thr(tBu)-OH (CAS 117106-20-4)
- Ethyl 1-amino-1H-pyrrole-3-carboxylate (CAS 941693-95-4)
- 3,3-Bis(4-hydroxyphenyl)-4,5,6,7-tetranitro-3H-benzo[c][1,2]oxathiole 1,1-dioxide (CAS 57564-54-2)
- 2-Methyl-2-(methylsulfonyl)propane (CAS 14094-12-3)
- 6-Thiomorpholinonicotinic acid (CAS 1042634-50-3)
- 3-Bromoimidazo[1,2-b]pyridazine (CAS 18087-73-5)
- Des-Ser34-Gly33Tirzepatide (CAS CATO-CPTD788941)
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