2,7-Dichloro-8-methylquinoline-3-carbonitrile CAS 948291-65-4
| CAS No. | 948291-65-4 |
| Molecular Formula | C11H6Cl2N2 |
| Molecular Weight | 237.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2,7-Dichloro-8-methylquinoline-3-carbonitrile (C11H6Cl2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 2,7-Dichloro-8-methylquinoline-3-carbonitrile (CAS 948291-65-4), a certified reference material (molecular formula C11H6Cl2N2, MW 237.08 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,7-Dichloro-8-methylquinoline-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H6Cl2N2 |
| Molecular Weight | 237.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- 4,8-Dichloro-6-methylquinoline-3-carbonitrile (CAS 1016759-71-9)
- 4,5-Dichloro-2-(3-methoxypropyl)pyridazin-3(2H)-one (CAS 1263216-11-0)
- 2,2-Dichloro-1(2H)-acenaphthylenone (CAS 13152-85-7)
- 5,6-Dichloro-3-isobutylpyrimidine-2,4(1H,3H)-dione (CAS 1708380-06-6)
- 2,4-Dichloro-6-methylquinoline-3-carbonitrile (CAS 749865-98-3)
- 2,4-Dichloro-8-methylquinoline-3-carbonitrile (CAS 2044274-76-0)
- 2,5-Dichloro-8-methylquinoline-3-carbonitrile (CAS 948291-30-3)
- 2,6-dichloro-7-prop-1-ynyl-quinoxaline (CAS 2644186-06-9)
Recommended Standards
- 2,6-Dichlorodibenzofuran (CAS 60390-27-4)
- 2,7-Dichlorodibenzofuran (CAS 74992-98-6)
- 2-Amino-5-fluorobenzeneboronic acid pinacol ester, 97% (CAS 863578-24-9)
- 2-Fluoro-5-methylpyridine-4-boronic acid pinacol eater (CAS 755027-42-0)
- 1-(4-Thiazolyl)ethylamine (CAS 885279-02-7)
- Tert-butyl ((5-aminobicyclo[3.2.1]Octan-1-yl)methyl)carbamate (CAS 2168968-23-6)
- 2-Bromo-3,5-dimethylthiophene (CAS 172319-76-5)
- 3-{[(2-chlorophenyl)methyl]sulfanyl}-5-methyl-1,2-thiazole-4-carbonitrile (CAS 339021-03-3)
- Dihydro Carveol (CAS 619-01-2)
- 4-[(Boc-amino)methyl]piperidine-4-methanol (CAS 493026-47-4)
- Amicarthiazol (CAS 21452-14-2)
- 2-((2-Methyl-1H-indol-3-yl)thio)-N-(p-tolyl)acetamide (CAS 536701-86-7)
- Tert-butyl 3-(3-hydroxybutan-2-yl)azetidine-1-carboxylate (CAS 2231675-36-6)
- Insulin Degludec Impurity 20 (CAS CATO-C4X-215720)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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