5-Bromo-2-fluoro-4-methoxybenzoic acid CAS 949014-42-0
| CAS No. | 949014-42-0 |
| Molecular Formula | C8H6BrFO3 |
| Molecular Weight | 249.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Bromo-2-fluoro-4-methoxybenzoic acid (CAS 949014-42-0), molecular formula C8H6BrFO3 and molecular weight 249.03 g/mol, is a CATO reference standard with documented purity and traceability.
5-Bromo-2-fluoro-4-methoxybenzoic acid (C8H6BrFO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 5-Bromo-2-fluoro-4-methoxybenzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6BrFO3 |
| Molecular Weight | 249.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
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- Methyl 5-bromo-2-fluoro-4-hydroxybenzoate (CAS 1142227-35-7)
- Methyl 4-bromo-2-fluoro-6-hydroxybenzoate, 97% (CAS 1193162-18-3)
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- 1-Bromo-2-ethynyl-4-(trifluoromethyl)benzene (CAS 1211523-00-0)
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Recommended Standards
- 4-Bromo-1-ethynyl-2-(trifluoromethyl)benzene (CAS 2244085-78-5)
- 5-Bromo-4-fluoro-2-methoxybenzoic acid (CAS 95383-26-9)
- 3-Bromo-5-fluoro-4-methoxybenzoic acid (CAS 445019-47-6)
- 6-Bromo-2-fluoro-3-methoxybenzoic acid (CAS 935534-45-5)
- 3-(3,5-Dichlorophenyl)-5,5-dimethyloxazolidine-2,4-dione (CAS 24201-58-9)
- Ethyl 2-oxo-1,2-dihydroquinoline-5-carboxylate (CAS 1261788-19-5)
- 4-(Dimethylamino)-2-methylenebutanoic acid hydrochloride (CAS 1989672-40-3)
- 5-Chloro-4'-(hydroxymethyl)-[1,1'-biphenyl]-3-carboxylic acid (CAS 1262005-64-0)
- 3-Amino-4-fluoro-n-methoxybenzamide (CAS 348165-47-9)
- 5-Chloro-2-(difluoromethyl)benzoic acid (CAS 1551365-62-8)
- 5-Methyl-1H-indazole-4-carbaldehyde (CAS 1783447-39-1)
- 1-Methyl-1H-pyrazole-4,5-diamine (CAS 45514-38-3)
- Ethyl 5-((2,6-dimethylphenyl)amino)-1,3-selenazole-4-carboxylate (CAS 197856-09-0)
- Tau Peptide (45-73) (Exon 2/Insert 1 Domain) trifluoroacetate salt (CAS 2022956-54-1)
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