4-(4-Chlorophenyl)-N-cyclopropyl-5-methylthiazol-2-amine CAS 949640-99-7

Description

4-(4-Chlorophenyl)-N-cyclopropyl-5-methylthiazol-2-amine (CAS 949640-99-7) is a high-purity analytical reference standard with the molecular formula C13H13ClN2S and a molecular weight of 264.77 g/mol.

The molecular framework of 4-(4-Chlorophenyl)-N-cyclopropyl-5-methylthiazol-2-amine (C13H13ClN2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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