4-Fluoro-2-hydroxypyrimidine CAS 950514-16-6

Purity 97%+In StockPharmaceutical Standards
CAS No.950514-16-6
Molecular FormulaC4H3FN2O
Molecular Weight114.08 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Fluoro-2-hydroxypyrimidine CAS 950514-16-6 chemical structure

Description

The occurrence of 4-Fluoro-2-hydroxypyrimidine is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 4-Fluoro-2-hydroxypyrimidine (CAS 950514-16-6), a certified reference material (molecular formula C4H3FN2O, MW 114.08 g/mol) for analytical method development and quality control.

The molecular framework of 4-Fluoro-2-hydroxypyrimidine (C4H3FN2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Fluoro-2-hydroxypyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC4H3FN2O
Molecular Weight114.08 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1987
Halogen ContentF-containing
Nitrogen Atoms2

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