2-Chloro-4,5-dimethoxyphenylboronic acid CAS 950662-22-3
| CAS No. | 950662-22-3 |
| Molecular Formula | C8H10BClO4 |
| Molecular Weight | 216.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Chloro-4,5-dimethoxyphenylboronic acid (CAS 950662-22-3), molecular formula C8H10BClO4 and molecular weight 216.43 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-4,5-dimethoxyphenylboronic acid (C8H10BClO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2-Chloro-4,5-dimethoxyphenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10BClO4 |
| Molecular Weight | 216.43 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
Related Chloro Standards
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- 2-Chloro-4-(methoxymethoxy)phenylboronic acid (CAS 1135992-31-2)
- 3-Chloro-2-(methoxymethoxy)phenylboronic acid (CAS 1256355-47-1)
- 2-Chloro-6-(methoxymethoxy)phenylboronic acid (CAS 1256355-51-7)
- 5-Chloro-2,4-dimethoxyphenylboronic acid (CAS 1393536-52-1)
- 3-Chloro-4-(methoxymethoxy)phenylboronic acid (CAS 1451392-27-0)
- 3-Chloro-4,5-dimethoxyphenylboronic acid (CAS 1701449-18-4)
- (3-Chloro-2,4-dimethoxyphenyl)boronic acid (CAS 750585-61-6)
Recommended Standards
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- (5-Chloro-2-(methoxymethoxy)phenyl)boronic acid (CAS 609352-56-9)
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- 2-methoxy-2-(2-methylphenyl)acetonitrile (CAS 1481965-07-4)
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