2,6-Difluoro-3-hydroxybenzamide CAS 951122-37-5
| CAS No. | 951122-37-5 |
| Molecular Formula | C7H5F2NO2 |
| Molecular Weight | 173.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,6-Difluoro-3-hydroxybenzamide (CAS 951122-37-5), molecular formula C7H5F2NO2 and molecular weight 173.12 g/mol, is a CATO reference standard with documented purity and traceability.
2,6-Difluoro-3-hydroxybenzamide (C7H5F2NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,6-Difluoro-3-hydroxybenzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5F2NO2 |
| Molecular Weight | 173.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 2-(3,5-Difluoro-2-pyridyl)acetic acid (CAS 1000518-01-3)
- 3,5-Difluoro-n-hydroxybenzamide (CAS 1016775-31-7)
- 2,5-Difluoro-1-methyl-3-nitrobenzene (CAS 1093758-82-7)
- 1,5-Difluoro-2-methyl-3-nitrobenzene (CAS 1188412-98-7)
- 3,5-Difluoro-4-hydroxybenzamide (CAS 1235892-52-0)
- 2,2-Difluoro-2-(pyridin-3-yl)acetic acid (CAS 1247461-08-0)
- 2,6-Difluoro-N-hydroxybenzamide (CAS 125309-34-4)
- 2,5-Difluoro-4-hydroxybenzamide (CAS 1261738-52-6)
Recommended Standards
- 2,3-Difluoro-1-methyl-4-nitrobenzene (CAS 932373-72-3)
- 2-Amino-3,6-difluorobenzoic acid (CAS 825654-54-4)
- 2-(Difluoromethoxy)nicotinaldehyde (CAS 2222104-51-8)
- 3-(2,5-Dioxooxazolidin-4-yl)propanoic acid (CAS 3981-39-3)
- 4-Ethyl-2-propylpyrimidine-5-carboxylic acid (CAS 1248250-14-7)
- 3H-Imidazo[4,5-b]pyridin-6-ol (CAS 1023815-26-0)
- 2-Bromo-4-ethynyl-1,3-difluorobenzene (CAS 2229219-28-5)
- Cis-tert-butyl 3-hydroxy-4-methyl-3-(trifluoromethyl)piperidine-1-carboxylate (CAS 1951444-40-8)
- 2-Amino-N-ethyl-N-((R)-1-methyl-piperidin-3-yl)-acetamide (CAS 1353996-30-1)
- Methyl 2-Furoylacetate (CAS 615-06-5)
- tert-butyl N-[rac-(1R,2S)-2-(4-aminophenyl)cyclopropyl]carbamate (CAS 1642574-86-4)
- (2R)-1-ethoxypropan-2-ol (CAS 609847-69-0)
- 7-Desdimethylamino-7-((2-(dimethylamino)ethyl)(methyl))amino)-Minocycline (CAS CATO-C4X-169935)
- Insulin Degludec Impurity 6 (CAS CATO-C4X-21576)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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