6-Methyl-4-(4-(trifluoromethyl)phenyl)pyridin-2-ol CAS 951231-44-0
| CAS No. | 951231-44-0 |
| Molecular Formula | C13H10F3NO |
| Molecular Weight | 253.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 6-Methyl-4-(4-(trifluoromethyl)phenyl)pyridin-2-ol is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 253.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
6-Methyl-4-(4-(trifluoromethyl)phenyl)pyridin-2-ol (CAS 951231-44-0) is a high-purity analytical reference standard with the molecular formula C13H10F3NO and a molecular weight of 253.22 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Methyl-4-(4-(trifluoromethyl)phenyl)pyridin-2-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10F3NO |
| Molecular Weight | 253.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 6-methyl-4-(trifluoromethyl)furo[2,3-b]pyridine-2-carboxylic acid (CAS 1049606-20-3)
- (4-(3-(Trifluoromethyl)pyridin-2-yl)phenyl)methanol (CAS 1092352-38-9)
- 6-Methyl-4-(2-(trifluoromethyl)phenyl)pyridin-2-ol (CAS 1261495-28-6)
- (3-(6-(Trifluoromethyl)pyridin-3-yl)phenyl)methanol (CAS 1356114-05-0)
- (5-Methyl-3-(trifluoromethyl)-1H-pyrrol-2-yl)(phenyl)methanone (CAS 142991-72-8)
- 3-(2-(Trifluoromethyl)phenyl)-5,6-dihydro-4H-pyrrolo[1,2-c][1,2,3]triazole (CAS 1445792-39-1)
- 4-Oxo-4-(4-(trifluoromethyl)piperidin-1-yl)butanoic acid (CAS 1477649-75-4)
- (5-Phenyl-4-(trifluoromethyl)pyridin-3-yl)methanol (CAS 1805022-65-4)
Recommended Standards
- 6-Methyl-4-(3-(trifluoromethyl)phenyl)pyridin-2-ol (CAS 442682-56-6)
- ethyl 2-(trifluoromethyl)-6H-furo[2,3-b]pyrrole-5-carboxylate (CAS 2640262-56-0)
- 6-(Trifluoromethyl)-2,3,4,9-tetrahydro-1H-carbazol-1-one (CAS 297763-74-7)
- Ethyl 4-(2,2,2-trifluoroethanimidoyl)piperazine-1-carboxylate (CAS 2201011-79-0)
- 3-Bromo-2,4-dimethylbenzaldehyde (CAS 693285-59-5)
- 2-{[3-cyano-6-ethyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinolin-2-yl]sulfanyl}-N-(3-methoxyphenyl)acetamide (CAS 664999-29-5)
- 4-Bromo-1-ethyl-1h-pyrazole-5-carbaldehyde (CAS 1001519-37-4)
- Ethyl 1-(4-cyanophenyl)-1H-pyrazole-3-carboxylate (CAS 1707392-21-9)
- N,N,N-Trimethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenaminium iodide (CAS 1218791-40-2)
- (Difluoromethyl)triphenylphosphonium bromide (CAS 58310-28-4)
- 5-Acetonyloxy-2-propyl-isoquinolin-1-one (CAS 906156-98-7)
- 1-BRomo-3-(isopropylsulfanyl)benzene (CAS 70398-87-7)
- (Z)-4-Hydroxytamoxifen (CAS 68047-06-3)
- Acetyl-Tau Peptide (273-284) amide trifluoroacetate salt (CAS 1684399-52-7)
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