tert-butyl 4-(5-bromothiophen-2-yl)piperidine-1-carboxylate CAS 951259-22-6
| CAS No. | 951259-22-6 |
| Molecular Formula | C14H20BrNO2S |
| Molecular Weight | 346.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including tert-butyl 4-(5-bromothiophen-2-yl)piperidine-1-carboxylate.
CATO supplies tert-butyl 4-(5-bromothiophen-2-yl)piperidine-1-carboxylate (CAS 951259-22-6), a certified reference material (molecular formula C14H20BrNO2S, MW 346.28 g/mol) for analytical method development and quality control.
The molecular framework of tert-butyl 4-(5-bromothiophen-2-yl)piperidine-1-carboxylate (C14H20BrNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H20BrNO2S |
| Molecular Weight | 346.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Recommended Standards
- N-Benzoyl-N-(2,3,4,5,6-pentafluorophenyl)thiourea (CAS 860609-73-0)
- 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2,4-triazolidine-3-thione (CAS 222408-90-4)
- N-[2-Nitro-4-(trifluoromethyl)phenyl]benzenesulfonamide (CAS 27188-62-1)
- [2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl] 2-methoxyacetate (CAS 1061604-95-2)
- 5-Bromo-2-methylbenzothiazole (CAS 63837-11-6)
- 3-(5-Styryl-1H-pyrazol-1-yl)tetrahydrothiophene 1,1-dioxide (CAS 321574-19-0)
- 4-Isopropyl-3-methylbenzaldehyde (CAS 40663-69-2)
- 2-((4-Amino-3-cyano-2-oxopent-3-en-1-yl)thio)acetic acid (CAS 885458-39-9)
- 4,5,6,7,9,9a,10,11,12,12a-Decahydrocyclopenta[c][1,4]diazepino[6,7,1-ij]quinoline hydrochloride (CAS 950818-28-7)
- (1-(4-Chlorophenyl)-1H-1,2,3-triazol-4-yl)methyl benzoate (CAS 338419-16-2)
- 2-(4-Chlorophenyl)-2,2-difluoroacetic Acid (CAS 475301-73-6)
- 3-Ethyl-7-methyloctahydro-2H-benzo[b][1,4]thiazine 1-oxide (CAS 1560007-09-1)
- Isamoltane Hemifumarate (CAS 874882-92-5)
- Peptide-GMF (CAS CATO-CPTD788469)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com