Tert-butyl 4-(2,6-difluorophenyl)piperazine-1-carboxylate CAS 951626-76-9
| CAS No. | 951626-76-9 |
| Molecular Formula | C15H20F2N2O2 |
| Molecular Weight | 298.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Tert-butyl 4-(2,6-difluorophenyl)piperazine-1-carboxylate (CAS 951626-76-9), molecular formula C15H20F2N2O2 and molecular weight 298.33 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Tert-butyl 4-(2,6-difluorophenyl)piperazine-1-carboxylate (C15H20F2N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Tert-butyl 4-(2,6-difluorophenyl)piperazine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H20F2N2O2 |
| Molecular Weight | 298.33 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl 3-(3,5-difluorophenyl)piperazine-1-carboxylate (CAS 886768-90-7)
- Tert-butyl 4-(3,4-difluorophenyl)piperazine-1-carboxylate (CAS 951626-88-3)
- Tert-butyl 3-(3,4-difluorophenyl)piperazine-1-carboxylate (CAS 886768-81-6)
- trans-2-Methyl-3-(5’-carboxy-3’-methyl-2’-pentenyl)-1,4-naphthoquinone (CAS 34185-71-2)
- n-((1,2,3-Thiadiazol-4-yl)methyl)cyclopropanamine (CAS 1156892-42-0)
- 2-(Piperazin-1-ylmethyl)-1H-benzimidazole dihydrochloride (CAS 1177362-39-8)
- 3-((Trifluoromethyl)thio)picolinamide (CAS 2385968-98-7)
- (S)-1-Thiazol-4-yl-ethylamine dihydrochloride (CAS 1965305-38-7)
- [6-[4-(Trifluoromethyl)phenyl]-3-pyridyl]methanol (CAS 356058-13-4)
- Benzo[e]pyrene-d12 (CAS 205440-82-0)
- 2,2,2-Trifluoroethyl n-[4-(2-methyl-6-oxo-1,6-dihydropyrimidin-4-yl)phenyl]carbamate (CAS 1354950-25-6)
- 8-Chloro-1-isopropyl-1H-[1,2,3]triazolo[4,5-h]quinazoline (CAS 2591612-04-1)
- 2-((3-Cyano-4,6-diphenylpyridin-2-yl)thio)-N-phenylacetamide (CAS 332040-65-0)
- D-Pro36-Tirzepatide (CAS CATO-CPTD788903)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com