(3-Chloro-4-methylphenyl)(3,4-difluorophenyl)methanone CAS 951891-00-2
| CAS No. | 951891-00-2 |
| Molecular Formula | C14H9ClF2O |
| Molecular Weight | 266.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies (3-Chloro-4-methylphenyl)(3,4-difluorophenyl)methanone (CAS 951891-00-2), a certified reference material (molecular formula C14H9ClF2O, MW 266.67 g/mol) for analytical method development and quality control.
The molecular framework of (3-Chloro-4-methylphenyl)(3,4-difluorophenyl)methanone (C14H9ClF2O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H9ClF2O |
| Molecular Weight | 266.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
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Recommended Standards
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- Methyl 3-iodo-1-methyl-1H-indazole-7-carboxylate (CAS 1337881-75-0)
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