N-(5-Chloro-2,4-dimethoxyphenyl)-2-cyanoacetamide CAS 952102-29-3
| CAS No. | 952102-29-3 |
| Molecular Formula | C11H11ClN2O3 |
| Molecular Weight | 254.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(5-Chloro-2,4-dimethoxyphenyl)-2-cyanoacetamide (CAS 952102-29-3), molecular formula C11H11ClN2O3 and molecular weight 254.67 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(5-Chloro-2,4-dimethoxyphenyl)-2-cyanoacetamide (C11H11ClN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(5-Chloro-2,4-dimethoxyphenyl)-2-cyanoacetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11ClN2O3 |
| Molecular Weight | 254.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
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- 1-(5-chloro-2-methoxy-phenyl)hexahydropyrimidine-2,4-dione (CAS 1062554-68-0)
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Recommended Standards
- N-(4-chloro-2,5-dimethoxyphenyl)-2-cyanoacetamide (CAS 549484-19-7)
- tert-Butyl 4-chloro-1H-pyrazolo[3,4-d]pyrimidine-1-carboxylate (CAS 943324-22-9)
- Methyl 7-chloro-5-(propan-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylate (CAS 99951-44-7)
- Baclofen Impurity 70 (CAS CATO-C4X-101270)
- N-Dodecane (CAS 112-40-3)
- 3-[(3-nitro-1h-pyrazol-1-yl)methyl]benzoic acid (CAS 402729-32-2)
- 4,5-Dibromophthaloyl dichloride (CAS 62366-73-8)
- 3-Bromo-5-methylbenzo[b]thiophene-2-carbaldehyde (CAS 50563-02-5)
- Imidaprilat-d3 (CAS 1356019-69-6)
- 2-Methyl-1-(1-methyl-1h-imidazol-2-yl)propan-2-ol (CAS 1506159-92-7)
- Ixazomib Impurity 53 (CAS CATO-C4X-126753)
- 2-Aminothiazole-5-carboxamide (CAS 52499-04-4)
- 1261570-91-5 4-Chloro-2-(trifluoromethoxy)phenylacetic acid MFCD18393873 (CAS 1261570-91-5)
- Liraglutide Impurity 19 TFA Salt (CAS CATO-C4X-199219)
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