2-Cyclobutyl-1-(4-fluorophenyl)quinazolin-4(1H)-one CAS 95216-39-0

Purity 97%+In StockPharmaceutical Standards
CAS No.95216-39-0
Molecular FormulaC17H13FN2O
Molecular Weight280.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Cyclobutyl-1-(4-fluorophenyl)quinazolin-4(1H)-one CAS 95216-39-0 chemical structure

Description

The occurrence of 2-Cyclobutyl-1-(4-fluorophenyl)quinazolin-4(1H)-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-Cyclobutyl-1-(4-fluorophenyl)quinazolin-4(1H)-one (CAS 95216-39-0), molecular formula C17H13FN2O and molecular weight 280.30 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 2-Cyclobutyl-1-(4-fluorophenyl)quinazolin-4(1H)-one (C17H13FN2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 280.30 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Cyclobutyl-1-(4-fluorophenyl)quinazolin-4(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC17H13FN2O
Molecular Weight280.30 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentF-containing
Nitrogen Atoms2

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