1-(4-Chlorophenyl)-2-cyclobutylquinazolin-4(1H)-one CAS 95216-42-5
| CAS No. | 95216-42-5 |
| Molecular Formula | C18H15ClN2O |
| Molecular Weight | 310.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(4-Chlorophenyl)-2-cyclobutylquinazolin-4(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 1-(4-Chlorophenyl)-2-cyclobutylquinazolin-4(1H)-one (CAS 95216-42-5), a certified reference material (molecular formula C18H15ClN2O, MW 310.78 g/mol) for analytical method development and quality control.
1-(4-Chlorophenyl)-2-cyclobutylquinazolin-4(1H)-one (C18H15ClN2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H15ClN2O |
| Molecular Weight | 310.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 4-(4-Chlorophenyl)-2-(4-methylpiperazin-1-yl)-4-oxobutanoic acid (CAS 139084-69-8)
- N-(2-Chlorophenyl)-7,7-dimethyl-6,8-dioxa-2-azaspiro[3.5]nonane-2-carboxamide (CAS 1396877-24-9)
- 2-((5-(4-Chlorophenyl)-1,3,4-thiadiazol-2-yl)amino)thiazol-4(5H)-one (CAS 89335-19-3)
- 4-((4-Chlorophenyl)amino)-4-oxo-3-(piperidin-1-yl)butanoic acid (CAS 708238-92-0)
- 5-(4-(3-Chlorophenyl)piperazin-1-yl)-5-oxopentanoic acid (CAS 551909-20-7)
- 5-(4-Chlorophenyl)-2-(2,3-dimethylphenoxy)pyrimidine (CAS 477890-44-1)
- N-(4-Chlorophenyl)-N-(2-methyl-1-naphthyl)urea (CAS 860610-52-2)
- 2-(4-chlorophenyl)-5-[(Z)-2-methoxy-2-phenylethenyl]furan 338786-41-7 6F-049 (CAS 338786-41-7)
Recommended Standards
- (3Z)-3-[(3-Chloro-4-methylphenyl)imino]-1-(prop-2-en-1-yl)-2,3-dihydro-1H-indol-2-one (CAS 338414-70-3)
- N-[1-(Aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-benzamide (CAS 1965308-76-2)
- 2-(Tert-butyl)-7-(4-chlorophenyl)-[1,2,4]triazolo[1,5-a]pyridine-8-carbonitrile (CAS 860611-04-7)
- TERT-BUTYL 4-(3-CHLOROPHENYL)-3-OXOPIPERAZINE-1-CARBOXYLATE (CAS 183500-69-8)
- 2-[2-(4-chlorophenoxy)acetyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 1007926-86-4)
- 2-Phenoxy-1-(4-(4-(thiophen-3-yl)thiazol-2-yl)piperazin-1-yl)propan-1-one (CAS 1448074-93-8)
- 1,4-Dibromo-2-fluoro-5-(trifluoromethoxy)benzene (CAS 1803785-48-9)
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- 1-(3,4-dihydro-2H-1-benzopyran-6-yl)ethan-1-amine hydrochloride (CAS 2031260-58-7)
- Ethyl 2-[4-[(1,1-dimethylethoxy)carbonyl]-1-piperazinyl]-1,6-dihydro-6-oxo-5-pyrimidinecarboxylate (CAS 1065074-31-8)
- Rac1 Inhibitor F56, control peptide (CAS 1315378-77-8)
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