5,7-Dichloro-2-methylthieno[3,2-b]pyridine CAS 952435-04-0
| CAS No. | 952435-04-0 |
| Molecular Formula | C8H5Cl2NS |
| Molecular Weight | 218.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5,7-Dichloro-2-methylthieno[3,2-b]pyridine (CAS 952435-04-0), molecular formula C8H5Cl2NS and molecular weight 218.10 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution, 5,7-Dichloro-2-methylthieno[3,2-b]pyridine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 218.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 5,7-Dichloro-2-methylthieno[3,2-b]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5Cl2NS |
| Molecular Weight | 218.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dichloro Standards
- 2,6-Dichloro-3-methylphenyl Isothiocyanate (CAS 1036587-85-5)
- 2,3-Dichloro-5-methylthieno[3,2-b]pyridine (CAS 170861-46-8)
- 1,3-Dichloro-2-(thiocyanatomethyl)benzene (CAS 7534-64-7)
- 1,5-Dichloro-2-isothiocyanato-3-methylbenzene (CAS 306935-83-1)
- 2,5-Dichloro-4-methyl-1,3-benzothiazole (CAS 887204-62-8)
- 2,6-Dichloro-4-methyl-1,3-benzothiazole (CAS 81561-05-9)
- 2,7-Dichloro-4-methyl-1,3-benzothiazole (CAS 80945-85-3)
- 4,5-Dichloro-2-methylbenzo[d]thiazole (CAS 40671-25-8)
Recommended Standards
- 5,6,7,8-Tetrafluoro-2H-chromen-2-one (CAS 33739-04-7)
- 5,7-Dichloro-3-methylthieno[3,2-b]pyridine (CAS 952435-06-2)
- 4,6-Dichloro-3-methylthieno[2,3-b]pyridine (CAS 2137806-76-7)
- 6-chloropyridine-2-sulfonyl chloride (CAS 913287-21-5)
- 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-cyclopropylacetamide (CAS 383148-41-2)
- 4-Hydroxypyrimidine-2-carbonitrile (CAS 1034827-34-3)
- (5-Bromofuran-2-yl)(morpholino)methanone (CAS 57785-37-2)
- Methyl 2-nitro-4-(trifluoromethoxy)benzoate (CAS 158579-87-4)
- 1-(4-Hydroxy-7-phenylthieno[3,2-d]pyrimidin-2-yl)-N-(2-morpholinoethyl)piperidine-3-carboxamide (CAS 1242864-59-0)
- (S)-2-(2-((dimethylamino)methyl)pyrrolidin-1-yl)acetic acid (CAS 1353994-95-2)
- Sodium 4-oxo-2-sulfonato-5,8,11,14-tetraoxahexacosanoate (CAS 40754-59-4)
- 1-(1-(4-Fluorophenyl)ethyl)piperazine hydrochloride (CAS 1185317-19-4)
- 6-(Dimethoxymethyl)-1H-pyrrolo[3,2-b]pyridine (CAS 1015609-43-4)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
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