1-(2-Bromo-4-methylphenyl)-1H-pyrrole-2-carboxylic acid CAS 952958-79-1
| CAS No. | 952958-79-1 |
| Molecular Formula | C12H10BrNO2 |
| Molecular Weight | 280.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(2-Bromo-4-methylphenyl)-1H-pyrrole-2-carboxylic acid (C12H10BrNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 1-(2-Bromo-4-methylphenyl)-1H-pyrrole-2-carboxylic acid (CAS 952958-79-1), a certified reference material (molecular formula C12H10BrNO2, MW 280.12 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10BrNO2 |
| Molecular Weight | 280.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-Bromo-N-(1-methyl-1H-pyrazol-3-yl)benzamide (CAS 1015523-19-9)
- 2-Bromo-1-(5-methyl-2-phenyloxazol-4-yl)ethan-1-one (CAS 103788-62-1)
- 2-Bromo-1-(5-methyl-3-phenylisoxazol-4-yl)ethan-1-one (CAS 104777-39-1)
- 3-((4-Bromo-1h-pyrazol-1-yl)methyl)benzamide (CAS 1179858-81-1)
- 6-Bromo-2,8-dimethylquinoline-3-carboxylic acid (CAS 1189106-75-9)
- 5-Bromo-1-(2-methylallyl)indoline-2,3-dione (CAS 122834-40-6)
- 4-Bromo-2-(3,5-dimethyl-1h-1,2,4-triazol-1-yl)benzaldehyde (CAS 1247910-61-7)
- 5-Bromo-2-(3-methoxyphenoxy)pyridine (CAS 1249147-55-4)
Recommended Standards
- (Z)-[(5-Bromofuran-2-yl)methyl](oxido)(phenylmethylidene)azanium (CAS 939893-18-2)
- 1-(3-Bromophenyl)-5-methyl-1H-pyrazole-3-carboxamide (CAS 784142-83-2)
- (5R,7S)-2-bromo-5-phenyl-6,7-dihydro-5H-pyrrolo[1,2-b][1,2,4]triazol-7-ol (CAS 2268741-27-9)
- 1-(4-Bromo-2-ethylphenyl)-1h-pyrrole-2,5-dione (CAS 431072-46-7)
- 3-Hydroxytetrahydrothiophene 1-oxide (CAS 92630-07-4)
- 2-(1-Ethyl-1H-1,2,3-triazol-4-yl)acetic acid hydrochloride (CAS 2137541-90-1)
- 1,2,3,4-Tetrahydroquinolin-6-amine (CAS 103796-41-4)
- N-1-Cyclohexyl-N-1-methyl-2-(trifluoromethyl)-1,4-benzenediamine (CAS 1183349-95-2)
- (4-Chloro-phenyl)-(1-methyl-7-trifluoromethyl-2,3-dihydro-1H-pyrido[2,3-b]pyrazin-4-yl)-methanone (CAS 1311278-09-7)
- 2-(3-Methylpiperidin-1-yl)pyrimidine-5-carboxylic acid (CAS 883543-69-9)
- 4-(2-(2-(3-(2-(3,3-Dimethyl-1-(4-sulfobutyl)indolin-2-ylidene)ethylidene)-2-(prop-2-yn-1-ylamino)cyclopent-1-en-1-yl)vinyl)-3,3-dimethyl-3H-indol-1-ium-1-yl)butane-1-sulfonate (CAS 1188292-54-7)
- Sodium 6-bromopyridine-2-sulfinate (CAS 2138422-74-7)
- 7-Methyl-4H-[1,2,5]oxadiazolo[3,4-b][1,4]diazepin-5(6H)-one (CAS 300588-18-5)
- (Ser(PO?H?)2?2)-Tau Peptide (260-264) PAb Blocking trifluoroacetate salt (CAS 2022956-57-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com