4-Methyl-2-(pyridin-4-yl)thiazole-5-carbonyl chloride hydrochloride CAS 953408-88-3
| CAS No. | 953408-88-3 |
| Molecular Formula | C10H7ClN2OS |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Methyl-2-(pyridin-4-yl)thiazole-5-carbonyl chloride hydrochloride (CAS 953408-88-3) is a high-purity analytical reference standard with the molecular formula C10H7ClN2OSHCl and a molecular weight of 275.15 g/mol.
The molecular framework of 4-Methyl-2-(pyridin-4-yl)thiazole-5-carbonyl chloride hydrochloride (C10H7ClN2OSHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Methyl-2-(pyridin-4-yl)thiazole-5-carbonyl chloride hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7ClN2OS HCl |
| Molecular Weight | 275.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methyl Standards
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- 4-(Pyridin-3-yloxy)benzenesulfonic acid (CAS 1000340-09-9)
- 2-(2-Oxo-2-(pyridin-4-yl)ethylidene)thiazolidin-4-one (CAS 1000932-15-9)
- 2-[2-oxo-2-(pyridin-3-yl)ethylidene]-1,3-thiazolidin-4-one (CAS 1000932-62-6)
- N-(pyridin-3-ylmethyl)sulfamide (CAS 1000933-31-2)
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Recommended Standards
- Ethyl 6-(tert-butyl)-4-chloronicotinate (CAS 1416439-99-0)
- N-(3-(Dibutylamino)phenyl)acetamide (CAS 77734-45-3)
- N-(4-Bromo-2,3-dichlorophenyl)acetamide (CAS 113571-16-7)
- 1-(3-(Trifluoromethyl)phenyl)-3-azabicyclo[3.1.0]Hexane (CAS 86215-49-8)
- 3,3'-(Perfluorocyclopent-1-ene-1,2-diyl)bis(5-bromo-2-methylthiophene) (CAS 159590-16-6)
- Pyrrolidin-3-ylmethanol (CAS 5082-74-6)
- 1-[3-(Trifluoromethyl)phenyl]cyclobutanecarbonitrile (CAS 29786-43-4)
- (R,R)-BaryPhos (CAS 2416226-97-4)
- 4,6-Dichloro-2-methylpyridazin-3(2H)-one (CAS 6885-89-8)
- Semaglutide impurity 26 (CAS CATO-C4X-222626)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com