2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)acetic acid CAS 95355-49-0
| CAS No. | 95355-49-0 |
| Molecular Formula | C8H5ClF3NO3 |
| Molecular Weight | 255.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)acetic acid (C8H5ClF3NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)acetic acid (CAS 95355-49-0), a certified reference material (molecular formula C8H5ClF3NO3, MW 255.58 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF3NO3 |
| Molecular Weight | 255.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-chloro-6-(2,2,2-trifluoroethoxy)pyridine-2-carboxylic acid (CAS 1021043-31-1)
- 3-Chloro-2-methoxy-5-(trifluoromethyl)isonicotinic acid (CAS 1221792-35-3)
- 1-(5-Chloro-2-nitrophenyl)-2,2,2-trifluoroethan-1-ol (CAS 1384243-41-7)
- 1-(4-Chloro-3-nitrophenyl)-2,2,2-trifluoroethan-1-ol (CAS 1554108-97-2)
- 4-Chloro-2-(methoxycarbonyl)-6-(trifluoromethyl)pyridine 1-oxide (CAS 1956356-35-6)
- 3-CHLORO-2-(METHOXYCARBONYL)-5-(TRIFLUOROMETHYL)PYRIDINE 1-OXIDE (CAS 1958091-84-3)
- (5-Chloro-2-nitro-4-(trifluoromethyl)phenyl)hydrazine (CAS 306935-07-9)
- 1-(4-Chloro-2-nitrophenyl)-2,2,2-trifluoroethanol (CAS 2228945-51-3)
Recommended Standards
- 1-Chloro-5-methoxy-4-nitro-2-(trifluoromethyl)benzene (CAS 646989-36-8)
- 2-[3-chloro-2-oxo-5-(trifluoromethyl)-1,2-dihydropyridin-1-yl]acetic acid (CAS 851208-01-0)
- 1-Chloro-3-nitro-5-(2,2,2-trifluoroethoxy)benzene (CAS 2092933-17-8)
- 2-Amino-3-chloro-5-(trifluoromethoxy)benzoic acid (CAS 433938-46-6)
- N-(2,2,2-Trifluoro-1-phenylethyl)benzamide (CAS 13652-10-3)
- 5-Methyl-1-oxo-2,5-diazaspiro[3.4]Octane-6-carboxylic acid (CAS 2182592-83-0)
- (R)-3-Methyl-5-(1-methylpyrrolidin-3-yl)isoxazole (CAS 226088-55-7)
- 4-Methylumbelliferyl N-acetyl-β-D-galactosaminide (CAS 36476-29-6)
- 2-Methyl-1-decanol (CAS 18675-24-6)
- 3-Fluoro-4-isopropoxy-5-(trifluoromethyl)benzoic acid (CAS 2624417-09-8)
- (2-Bromobenzyl)(4-fluorophenyl)sulfane (CAS 1001161-72-3)
- (2E)-3-(2H-1,3-Benzodioxol-5-yl)-N-(4-phenoxyphenyl)prop-2-enamide (CAS 298215-73-3)
- PEG3-C4-OBn (CAS 2381196-79-6)
- Semaglutide impurity 259 (CAS CATO-C4X-2226259)
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