5-(2,5-Difluorophenyl)isoxazole-3-carboxylic Acid CAS 953735-19-8
| CAS No. | 953735-19-8 |
| Molecular Formula | C10H5F2NO3 |
| Molecular Weight | 225.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-(2,5-Difluorophenyl)isoxazole-3-carboxylic Acid (C10H5F2NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5-(2,5-Difluorophenyl)isoxazole-3-carboxylic Acid (CAS 953735-19-8) is a high-purity analytical reference standard with the molecular formula C10H5F2NO3 and a molecular weight of 225.15 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-(2,5-Difluorophenyl)isoxazole-3-carboxylic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H5F2NO3 |
| Molecular Weight | 225.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluorophenyl Standards
- 5-(3,4-Difluorophenyl)isoxazole-3-carboxylic Acid (CAS 1017513-51-7)
- 1-(3,5-Difluorophenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1038261-56-1)
- 1-(3,4-Difluorophenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1038261-86-7)
- 5-(2,4-Difluorophenyl)isoxazole-3-carboxylic Acid (CAS 1083224-23-0)
- 3-(2,3-Difluorophenyl)isoxazole-5-carboxylic acid (CAS 1126636-77-8)
- 3-(2,6-Difluorophenyl)-1,2-oxazole-5-carboxylic acid (CAS 1152531-95-7)
- 1-(3,5-Difluorophenyl)-1h-1,2,3-triazole-5-carboxylic acid (CAS 1153490-77-7)
- 5-(2,6-Difluorophenyl)isoxazole-3-carboxylic Acid (CAS 1188054-32-1)
Recommended Standards
- 4-Methyl-6-nitrobenzo[d][1,3]dioxole-5-carboxylic acid (CAS 861588-35-4)
- 5-(3,5-Difluorophenyl)-1,3-oxazole-4-carboxylic acid (CAS 887267-63-2)
- 4-(Methoxycarbonyl)-2-nitrobenzoic acid (CAS 55737-66-1)
- 5-(3,5-Difluorophenyl)isoxazole-3-carboxylic Acid (CAS 885958-97-4)
- N-cyclopropylpiperazine-1-carboxamide Hydrochloride (CAS 1225500-01-5)
- 1-(2-Fluorophenyl)-3-methylurea (CAS 13140-07-3)
- 9-(2-Ethoxy-1,3-dioxan-5-yl)-9H-purin-6-amine (CAS 88778-16-9)
- N-(Thiophen-2-ylmethyl)ethanamine hydrochloride (CAS 116600-48-7)
- 3-Iodo-4-(trifluoromethyl)benzaldehyde (CAS 372120-53-1)
- n-(2-((2-Bromobenzyl)amino)ethyl)acetamide (CAS 1042541-42-3)
- 3-Chloro-4-(5-oxo-3-(p-tolyl)imidazolidin-1-yl)benzenesulfonamide (CAS 53298-05-8)
- tert-Butyl 3-(4-(aminomethyl)-1H-1,2,3-triazol-1-yl)azetidine-1-carboxylate hydrochloride (CAS 2137640-21-0)
- 5-Bromo-3-methyl-2-(morpholino)pyridine (CAS 566158-47-2)
- Thymopoietin II Peptide Fragment (CAS 56795-64-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com