6-Fluoro-5-nitro-2,3-dihydro-1H-indole-2,3-dione CAS 953751-33-2
| CAS No. | 953751-33-2 |
| Molecular Formula | C8H3FN2O4 |
| Molecular Weight | 210.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-Fluoro-5-nitro-2,3-dihydro-1H-indole-2,3-dione (C8H3FN2O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
6-Fluoro-5-nitro-2,3-dihydro-1H-indole-2,3-dione (CAS 953751-33-2), molecular formula C8H3FN2O4 and molecular weight 210.12 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Fluoro-5-nitro-2,3-dihydro-1H-indole-2,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H3FN2O4 |
| Molecular Weight | 210.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 7-fluoro-5-nitro-2,3-dihydro-1H-indole-2,3-dione (CAS 1176058-71-1)
- 5-Fluoro-7-nitro-2,3-dihydro-1h-indole-2,3-dione (CAS 954571-39-2)
- 3-Fluoro-5-(2,2,2-trifluoroethoxy)phenol (CAS 1026796-69-9)
- (5-Fluoro-2-(trifluoromethoxy)phenyl)methanol (CAS 1092460-86-0)
- (2-Fluoro-4-(trifluoromethoxy)phenyl)methanol (CAS 1240257-07-1)
- (4-Fluoro-2-(trifluoromethoxy)phenyl)methanol (CAS 1242252-68-1)
- 4-Fluoro-5-(trifluoromethoxy)benzene-1,2-diamine (CAS 1804386-40-0)
- 4-Fluoro-3-(2,2,2-trifluoroethoxy)phenol (CAS 1881290-53-4)
Recommended Standards
- Cyclohexylboronic Acid Pinacol Ester (CAS 87100-15-0)
- 5-Bromo-2-(methylsulfanyl)-1,3-thiazole (CAS 956293-02-0)
- rel-2-((1R,2R)-2-Isopropylcyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2375816-13-8)
- 5-Benzylidene-2-thioxodihydropyrimidine-4,6(1H,5H)-dione (CAS 27470-61-7)
- 2-(1-Ethyl-piperidin-4-yl)-2H-pyrazol-3-ylamine (CAS 957005-84-4)
- Lenperone (CAS 24678-13-5)
- 1-Ethoxy-4-fluoro-2-nitrobenzene (CAS 321-04-0)
- tert-Butyl 3-hydroxy-4-oxopiperidine-1-carboxylate (CAS 1130156-23-8)
- 5-Amino-1-(cyclopentylmethyl)pyrimidine-2,4(1h,3h)-dione (CAS 1339792-78-7)
- 3-benzyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-2,5-dione (CAS 10167-35-8)
- 7-Fluoro-1H-indol-4-amine (CAS 1360922-65-1)
- Papaverine Impurity 17 (CAS 18783-43-2)
- 2-(1-Methyl-5-nitro-1H-imidazol-2-yl)-5-(propylthio)-1,3,4-thiadiazole (CAS 207236-20-2)
- MCH-Gene-Overprinted-Polypeptide-14 (rat) (H-4746.0500) (CAS 182917-44-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com