1-(3-Chlorophenyl)-3-(diethylamino)pyrrolidine-2,5-dione CAS 95498-44-5
| CAS No. | 95498-44-5 |
| Molecular Formula | C14H17ClN2O2 |
| Molecular Weight | 280.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(3-Chlorophenyl)-3-(diethylamino)pyrrolidine-2,5-dione.
CATO supplies 1-(3-Chlorophenyl)-3-(diethylamino)pyrrolidine-2,5-dione (CAS 95498-44-5), a certified reference material (molecular formula C14H17ClN2O2, MW 280.75 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 1-(3-Chlorophenyl)-3-(diethylamino)pyrrolidine-2,5-dione is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 280.75 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(3-Chlorophenyl)-3-(diethylamino)pyrrolidine-2,5-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H17ClN2O2 |
| Molecular Weight | 280.75 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 1-{4-[(4-Chlorophenyl)thio]-3-fluorophenyl}ethanone (CAS 1030429-38-9)
- 1-(4-(4-Acetyl-2-chlorophenyl)piperazin-1-yl)ethan-1-one (CAS 1283466-18-1)
- Ethyl 1-(2-Chlorophenyl)-4-oxocyclohexanecarboxylate (CAS 1385694-52-9)
- 1-(4-Chlorophenyl)-3-(4-fluorophenyl)thiourea (CAS 370-26-3)
- 1-[2-(4-chlorophenyl)-2-oxoethyl]piperidine-4-carboxamide (CAS 946817-32-9)
- 6-(4-Chlorophenyl)-4-(2-hydroxybutyl)-4,5-dihydropyridazin-3(2H)-one (CAS 38958-82-6)
- cis-2-[2-(2-Chlorophenyl)-2-oxoethyl]-cyclohexane-1-carboxylic acid (CAS 736136-45-1)
- cis-4-[2-(2-Chlorophenyl)-2-oxoethyl]-cyclohexane-1-carboxylic acid (CAS 735275-63-5)
Recommended Standards
- 1-(2-Chloroacetyl)-n-phenylpiperidine-4-carboxamide (CAS 923171-84-0)
- (R)-2-chloro-8-cyclopentyl-7-ethyl-7,8-dihydropteridin-6(5H)-one (CAS 755039-54-4)
- 1-(6-Chloropyridazin-3-yl)-N-(prop-2-en-1-yl)piperidine-4-carboxamide (CAS 339276-40-3)
- (1S,3R)-3-(2-(4-chlorophenyl)-2-oxoethyl)cyclohexane-1-carboxylic acid (CAS 735275-17-9)
- CycLuc 1 (CAS 1247879-16-8)
- (3S,5S,6R)-tert-Butyl 3-bromo-2-oxo-5,6-diphenylmorpholine-4-carboxylate (CAS 112741-51-2)
- 3-Amino-N-(3-chloro-phenyl)-4-methyl-benzenesulfonamide (CAS 326023-04-5)
- 1-(4-Chlorophenyl)pyrrolidine-2-thione (CAS 58973-25-4)
- Ethyl 5-(4-chlorophenyl)-1h-1,2,4-triazole-3-carboxylate (CAS 62230-51-7)
- (2S)-2-(4-bromophenoxy)propanoic acid (CAS 37819-43-5)
- 4-((M-tolyloxy)methyl)piperidine hydrochloride (CAS 614731-24-7)
- (4AR,6S,7R,8S,8aR)-6-methoxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxine-7,8-diyl diacetate (CAS 4141-45-1)
- 3-(Methylthio)-4-nitroaniline (CAS 31911-44-1)
- Peptide Impurity 34 (CAS 21282-09-7)
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